Detectable thyroglobulin with negative imaging in differentiated thyroid cancer patients What to do with negative anatomical imaging and radioiodine scan?

被引：3
|
作者：
Giovanella, L. [1 ,2 ]
Treglia, G. [1 ,2 ]
Ceriani, L. [1 ,2 ]
Verburg, F. [3 ,4 ]
机构：
[1] Oncol Inst Southern Switzerland, Dept Nucl Med, CH-6500 Bellinzona, Switzerland
[2] Oncol Inst Southern Switzerland, Thyroid Ctr, CH-6500 Bellinzona, Switzerland
[3] Univ Aachen, Dept Nucl Med, Aachen, Germany
[4] Maastricht Univ, Dept Nucl Med, Med Ctr, Maastricht, Netherlands
来源：
NUKLEARMEDIZIN-NUCLEAR MEDICINE | 2014年 / 53卷 / 01期
关键词：
Differentiated thyroid carcinoma; thyroglobulin; whole body scan; positron emission tomography; WHOLE-BODY SCAN; ELEVATED SERUM THYROGLOBULIN; POSITRON-EMISSION-TOMOGRAPHY; LINKED-IMMUNOSORBENT-ASSAY; FOLLOW-UP; CARCINOMA PATIENTS; LYMPH-NODE; HETEROPHILE ANTIBODIES; DIAGNOSTIC-VALUE; DOUBLING-TIME;
D O I：
10.3413/Nukmed-0618-13-08
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
In the absence of autoantibodies against thyroglobulin (Tg), Tg measurement nowadays is the cornerstone of clinical management of differentiated thyroid cancer patients. DTC patients presenting with a positive Tg measurement without an anatomical correlate on anatomic imaging provide a management challenge to the attending physician. Based on the literature we will provide an overview of the most important steps to undertake in such patients and their potential clinical consequences.
引用
收藏
页码：1 / 10
页数：10
相关论文
共 50 条
  • [1] Management of Differentiated Thyroid Cancer with Rising Thyroglobulin and Negative Diagnostic Radioiodine Whole Body Scan
    Chao, M.
    [J]. CLINICAL ONCOLOGY, 2010, 22 (06) : 438 - 447
  • [2] Approach to the patient with a positive serum thyroglobulin and a negative radioiodine scan after initial therapy for differentiated thyroid cancer
    Kloos, Richard T.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2008, 93 (05): : 1519 - 1525
  • [3] Pathological evaluation of differentiated thyroid cancer in patients with positive serum thyroglobulin and negative iodine scan
    Ansari, M.
    Babaei, A. A.
    Shafiei, B.
    Javadi, H.
    Assadi, M.
    Nabipour, I.
    Asli, I. N.
    [J]. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2014, 18 (13) : 1925 - 1929
  • [4] High therapeutic dosages of radioiodine in differentiated thyroid cancer patients with detectable serum thyroglobulin.
    de Keizer, B
    de Klerk, JM
    Koppeschaar, HP
    Zelissen, PM
    Lips, CM
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2000, 41 (05) : 308P - 308P
  • [5] Octreotide scintigraphy in patients with differentiated thyroid carcinoma: Contribution for patients with negative radioiodine scan
    Baudin, E
    Schlumberger, M
    Lumbroso, J
    Travagli, JP
    Caillou, B
    Parmentier, C
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1996, 81 (07): : 2541 - 2544
  • [6] Nuclear medicine imaging procedures in differentiated thyroid carcinoma patients with negative iodine scan
    Rubello, D
    Saladini, G
    Carpi, A
    Casara, D
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2000, 54 (06) : 337 - 344
  • [7] Results of Rosiglitazone Therapy in Patients with Thyroglobulin-Positive and Radioiodine-Negative Advanced Differentiated Thyroid Cancer
    Kebebew, Electron
    Lindsay, Sheila
    Clark, Orlo H.
    Woeber, Kenneth A.
    Hawkins, Randall
    Greenspan, Francis S.
    [J]. THYROID, 2009, 19 (09) : 953 - 956
  • [8] A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer
    Kebebew, Electron
    Peng, Miao
    Reiff, Emily
    Treseler, Patrick
    Woeber, Kenneth A.
    Clark, Orlo H.
    Greenspan, Francis S.
    Lindsay, Sheila
    Duh, Quan-Yang
    Morita, Eugene
    [J]. SURGERY, 2006, 140 (06) : 960 - 966
  • [9] Rosiglitazone in two patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer:: preliminary results
    Martin, Tomas
    Torres, Alberto
    Cambil, Teresa
    Castro, Juan
    [J]. MEDICINA CLINICA, 2008, 131 (11): : 435 - 435
  • [10] Outcome in patients with differentiated thyroid cancer with negative diagnostic whole-body scanning and detectable stimulated thyroglobulin
    van Tol, KM
    Jager, PL
    de Vries, EGE
    Piers, DA
    Boezen, HM
    Sluiter, WJ
    Dullaart, RPF
    Links, TP
    [J]. EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2003, 148 (06) : 589 - 596
12345