Analyses of anticancer drugs by capillary electrophoresis: a review

被引：55
|
作者：
Ali, Imran [1 ]
Haque, Ashanul [1 ]
Wani, Waseem A. [1 ]
Saleem, Kishwar [1 ]
Al Za'abi, Mohammed [2 ]
机构：
[1] Jamia Millia Islamia, Dept Chem, New Delhi 110025, India
[2] Sultan Qaboos Univ, Dept Pharmacol & Clin Pharm, Coll Med & Hlth Sci, Muscat, Oman
来源：
BIOMEDICAL CHROMATOGRAPHY | 2013年 / 27卷 / 10期
关键词：
capillary electrophoresis; anticancer drugs; biological samples; future perspectives; POTENTIAL TUMOR-MARKERS; DNA METHYLATION; BREAST-CANCER; HUMAN PLASMA; SIMULTANEOUS QUANTIFICATION; ZONE-ELECTROPHORESIS; URINARY NUCLEOSIDES; PROTEIN-BINDING; VINCA ALKALOIDS; GASTRIC-CANCER;
D O I：
10.1002/bmc.2953
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Capillary electrophoresis is a fast, inexpensive and low detection limit technique for the analysis of anticancer drugs. It has been used to analyze various anticancer drugs in biological samples, pharmaceutical preparations and environmental matrices. It has also been used to detect various cancer biomarkers in cancer patients. The present article describes the state-of-the art of capillary electrophoresis for the analyses of anticancer drugs. Various drugs discussed belong to several groups such as antimitotic agents, nucleoside analogs, antibiotics, topoisomerase inhibitors and DNA intercalating agents. In addition, efforts have also been made to discuss sample preparation, applications of capillary electrophoresis in genomic research, optimization and future perspectives. Copyright (c) 2013 John Wiley & Sons, Ltd.
引用
收藏
页码：1296 / 1311
页数：16
相关论文
共 50 条
  • [1] Analysis of traditional Chinese anticancer drugs by capillary electrophoresis
    Liebich, HM
    Lehmann, R
    Di Stefano, C
    Häring, HU
    Kim, JH
    Kim, KR
    JOURNAL OF CHROMATOGRAPHY A, 1998, 795 (02) : 388 - 393
  • [2] Capillary electrophoresis for the analysis of antidepressant drugs: A review
    Keyon, Aemi Syazwani Abdul
    Miskam, Mazidatulakmam
    Ishak, Nur Syazwani
    Mahat, Naji Arafat
    Huri, Mohamad Afiq Mohamed
    Wahab, Roswanira Abdul
    Chandren, Sheela
    Razak, Fazira Ilyana Abdul
    Nyuk-Ting Ng
    Ali, Timothy Gandu
    JOURNAL OF SEPARATION SCIENCE, 2019, 42 (04) : 906 - 924
  • [3] Capillary electrophoresis as a versatile tool for the bioanalysis of drugs - a review
    Boone, CM
    Waterval, JCM
    Lingeman, H
    Ensing, K
    Underberg, WJM
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1999, 20 (06) : 831 - 863
  • [4] Analyses of quaternary ammonium drugs in horse urine by capillary electrophoresis - mass spectrometry
    Tang, FPW
    Leung, GNW
    Wan, TSM
    ELECTROPHORESIS, 2001, 22 (11) : 2201 - 2209
  • [5] Capillary electrophoresis of cardiovascular drugs
    Nguyen, NT
    Siegler, RW
    JOURNAL OF CHROMATOGRAPHY A, 1996, 735 (1-2) : 123 - 150
  • [6] EVALUATION OF ANTICANCER DRUGS BY LYMPHOCYTE ELECTROPHORESIS
    HAYASHI, H
    TOYAMA, N
    FUJII, T
    FUJII, M
    YOSHIKUMI, C
    KAWAI, Y
    IWAGUCHI, T
    JOURNAL OF PHARMACOBIO-DYNAMICS, 1986, 9 (09): : 729 - 736
  • [7] Capillary electrophoresis methods for impurity profiling of drugs: A review of the past decade
    Mansi Shah
    Nrupesh Patel
    Nagja Tripathi
    Vivek K.Vyas
    JournalofPharmaceuticalAnalysis, 2022, 12 (01) : 15 - 28
  • [8] Capillary electrophoresis methods for impurity profiling of drugs: A review of the past decade
    Shah, Mansi
    Patel, Nrupesh
    Tripathi, Nagja
    Vyas, Vivek K. K.
    JOURNAL OF PHARMACEUTICAL ANALYSIS, 2022, 12 (01) : 15 - 28
  • [9] A REVIEW ON ELECTROPHORESIS, CAPILLARY ELECTROPHORESIS AND HYPHENATIONS
    Gummadi, S.
    Kandula, V. N.
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2020, 11 (12): : 6038 - 6056
  • [10] Monitoring anticancer drug metabolism with capillary electrophoresis
    Jones, Amanda M.
    Subramaniam, Varuni
    Haes, Amanda J.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 240
12345