Spontaneous regression of a congenital high-grade glioma-a case report

被引：3

作者：

Riedmeier, Maria ^{[1
]}

Stock, Annika ^{[2
,3
]}

Krauss, Juergen ^{[3
,4
]}

Sahm, Felix ^{[5
,6
]}

Jones, David T. W. ^{[7
,8
]}

Sturm, Dominik ^{[7
,9
]}

Kramm, Christof M. ^{[10
]}

Eyrich, Matthias ^{[1
,3
,11
]}

Haertel, Christoph ^{[1
,3
]}

Schlegel, Simon ^{[1
,12
]}

Schlegel, Paul Gerhardt ^{[1
,3
,11
]}

Monoranu, Camelia-Maria ^{[3
]}

Wiegering, Verena ^{[1
,3
]}

机构：

[1] Univ Wurzburg, Univ Childrens Hosp, Dept Pediat Hematol Oncol & Stem Cell Transplanta, Josef Schneiderstr 2, D-97080 Wurzburg, Germany

[2] Univ Wurzburg, Univ Hosp, Dept Neuroradiol, Wurzburg, Germany

[3] Univ Wurzburg, Comprehens Canc Ctr Mainfranken, Med Ctr, Wurzburg, Germany

[4] Univ Wurzburg, Univ Childrens Hosp, Dept Pediat Neurosurg, Wurzburg, Germany

[5] Univ Hosp Heidelberg, Dept Neuropathol, Heidelberg, Germany

[6] German Canc Res Ctr, Clin Cooperat Unit Neuropathol, German Canc Consortium DKTK, Heidelberg, Germany

[7] Hopp Childrens Canc Ctr KiTZ, Heidelberg, Germany

[8] German Canc Res Ctr, Heidelberg, Germany

[9] German Canc Res Ctr, Div Pediat Neurooncol, German Canc Consortium DKTK, Heidelberg, Germany

[10] Univ Gottingen, Univ Med Ctr Gottingen, Div Pediat Hematol & Oncol, Gottingen, Germany

[11] Univ Wurzburg, Bavarian Canc Res Ctr BZKF, Wurzburg, Germany

[12] Semmelweis Univ, Budapest, Hungary

来源：

NEURO-ONCOLOGY ADVANCES | 2021年 / 3卷 / 01期

关键词：

D O I：

10.1093/noajnl/vdab120

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Congenital anaplastic astrocytomas and glioblastomas (cGBMs) are rare tumors of the central nervous system. 1 Most cGBMs are histologically indistinguishable from GBM in older children and adults but may have a more favorable outcome, suggesting biological and molecular differences. We describe a case of spontaneous regression of a cGBM with molecular evidence of a CLIP2-MET fusion.

引用

页数：4

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