Non-immunodominant CD8+ T-cell responses can be harnessed to mount antitumor immunity in the tolerant HER-2/neu transgenic mice

被引:0
|
作者
Uram, Jennifer [1 ]
Black, Chelsea [1 ]
Flynn, Emilee [1 ]
Huang, Lanqing [1 ]
Armstrong, Todd [1 ]
Jaffee, Elizabeth [1 ]
机构
[1] Johns Hopkins Univ, Baltimore, MD USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4165
引用
收藏
页数:1
相关论文
共 50 条
  • [1] The CD8+ T cell repertoire against Her-2/neu antigens in neu transgenic mice is of low avidity with antitumor activity
    Lustgarten, J
    Dominguez, AL
    Cuadros, C
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2004, 34 (03) : 752 - 761
  • [2] Immunization with a HER-2/neu helper peptide generates HER-2/neu CD8 T-cell immunity in cancer patients
    Knutson, KL
    Schiffman, K
    Disis, ML
    JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (04): : 477 - 484
  • [3] Breast Cancer Neoantigens Can Induce CD8+ T-Cell Responses and Antitumor Immunity
    Zhang, Xiuli
    Kim, Samuel
    Hundal, Jasreet
    Herndon, John M.
    Li, Shunqiang
    Petti, Allegra A.
    Soysal, Savas D.
    Li, Lijin
    McLellan, Mike D.
    Hoog, Jeremy
    Primeau, Tina
    Myers, Nancy
    Vickery, Tammi L.
    Sturmoski, Mark
    Hagemann, Ian S.
    Miller, Chris A.
    Ellis, Matthew J.
    Mardis, Elaine R.
    Hansen, Ted
    Fleming, Timothy P.
    Goedegebuure, S. Peter
    Gillanders, William E.
    CANCER IMMUNOLOGY RESEARCH, 2017, 5 (07) : 516 - 523
  • [4] Comparing CD8+ T cell repertoires in non-tolerant FVB/N and tolerant HER-2/neutransgenic mice
    Uram, Jennifer N.
    Ercolini, Anne M.
    Pfannenstiel, Luke
    Armstrong, Todd D.
    Jaffee, Elizabeth M.
    CANCER RESEARCH, 2006, 66 (08)
  • [5] Adjuvant effect of HER-2/neu-specific adenoviral vector stimulating CD8+ T and natural killer cell responses on anti-HER-2/neu antibody therapy for well-established breast tumors in HER-2/neu transgenic mice
    Chen, Y.
    Xie, Y.
    Chan, T.
    Sami, A.
    Ahmed, S.
    Liu, Q.
    Xiang, J.
    CANCER GENE THERAPY, 2011, 18 (07) : 489 - 499
  • [6] Adjuvant effect of HER-2/neu-specific adenoviral vector stimulating CD8+ T and natural killer cell responses on anti-HER-2/neu antibody therapy for well-established breast tumors in HER-2/neu transgenic mice
    Y Chen
    Y Xie
    T Chan
    A Sami
    S Ahmed
    Q Liu
    J Xiang
    Cancer Gene Therapy, 2011, 18 : 489 - 499
  • [7] Natural CD8+ T-cell responses against MHC class I epitopes of the HER-2/neu oncoprotein in patients with epithelial tumors
    Panagiota A. Sotiropoulou
    Sonia A. Perez
    Volfgang Voelter
    Hartmut Echner
    Ioannis Missitzis
    Nick B. Tsavaris
    Michael Papamichail
    Constantin N. Baxevanis
    Cancer Immunology, Immunotherapy, 2003, 52 : 771 - 779
  • [8] Natural CD8+ T-cell responses against MHC class I epitopes of the HER-2/neu oncoprotein in patients with epithelial tumors
    Sotiropoulou, PA
    Perez, SA
    Voelter, V
    Echner, H
    Missitzis, I
    Tsavaris, NB
    Papamichail, M
    Baxevanis, CN
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2003, 52 (12) : 771 - 779
  • [9] Remodeling Translation Primes CD8+ T-cell Antitumor Immunity
    Hurst, Katie E.
    Lawrence, Kiley A.
    Robino, Rob A.
    Ball, Lauren E.
    Chung, Dongjun
    Thaxton, Jessica E.
    CANCER IMMUNOLOGY RESEARCH, 2020, 8 (05) : 587 - 595
  • [10] CD40L+ CD8+ T-Cell Dependent Antitumor Immunity
    Thiel, Andreas
    Frentsch, Marco
    Listopad, Joanna
    Stark, Regina
    Japp, Alberto Sada
    Matzmohr, Nadine
    Meier, Sarah
    Taniuchi, Ichiro
    Blankenstein, Thomas
    BLOOD, 2014, 124 (21)