An Expedient Synthesis of 2,4,6-Tris(trifluoromethyl)aniline

被引：0
|
作者：
Edelbach, Brian L. [2 ]
Pharoah, Blaze M. [2 ]
Bellows, Sarina M. [1 ]
Thayer, Peter R. [2 ]
Fennie, Charles N. [2 ]
Cowley, Ryan E. [1 ]
Holland, Patrick L. [1 ]
机构：
[1] Univ Rochester, Dept Chem, Rochester, NY 14627 USA
[2] SUNY Monroe Community Coll, Rochester, NY 14623 USA
来源：
SYNTHESIS-STUTTGART | 2012年 / 44卷 / 23期
基金：
美国国家科学基金会;
关键词：
fluorination; aniline; ligand precursor; LIGANDS; COMPLEXES; CATALYSTS;
D O I：
10.1055/s-0032-1316809
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple two-step synthetic route leads to 2,4,6-tris(trifluoromethyl) aniline. It proceeds through deprotonation and iodination of 1,3,5-tris(trifluoromethyl) benzene, followed by copper-catalyzed amination.
引用
收藏
页码：3595 / 3597
页数：3
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