Implementing Genome-Informed Personalized Medicine in the US Air Force Medical Service via the Patient-Centered Precision Care Research (PC2-Z) Program

被引：0

作者：

Bradburne, Christopher E. ^{[1
,2
]}

Carruth, Lucy M. ^{[1
,2
]}

Lin, Jeffrey S. ^{[3
]}

Sivakumar, Ashok ^{[3
,4
]}

Benson, John H. ^{[3
,5
]}

Vogel, Ruth A. ^{[2
,3
]}

机构：

[1] Johns Hopkins Univ, Appl Phys Lab, Asymmetr Operat Dept, Laurel, MD 20703 USA

[2] Johns Hopkins Univ, Appl Phys Lab, PC2 Z Program, Laurel, MD 20703 USA

[3] Johns Hopkins Univ, Appl Phys Lab, REDD, Laurel, MD 20703 USA

[4] Johns Hopkins Univ, Appl Phys Lab, CUS, Laurel, MD 20703 USA

[5] Johns Hopkins Univ, Appl Phys Lab, PC2 Z Project, Laurel, MD 20703 USA

来源：

JOHNS HOPKINS APL TECHNICAL DIGEST | 2013年 / 31卷 / 04期

关键词：

D O I：

暂无

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Personal genomic information is poised to revolutionize medicine and provide patients with increasingly individualized medical care. Advances in genomic typing and sequencing technologies are making access to inexpensive, personal genomic information a rapidly evolving reality. However, the effective integration of genomic information into clinical care will pose many logistical, ethical, and legal challenges moving forward. In response to this rapidly evolving health care revolution, the U.S. Air Force (USAF) has established the Patient-Centered Precision Care Research (PC2-Z) Program. The aim of this program is to evaluate the clinical impact of genome-informed care and to begin to lay the foundation for its implementation in the USAF. The PC2-Z program's overarching goal is to gather clinical knowledge and provide recommendations for translating genome-informed medicine into personalized health care for DoD personnel and beneficiaries. APL is serving as the program integrator for this ground-breaking program, bringing together the government, academic, and industry partners to implement program focus areas in research, bioinformatics, education, and policy. A centerpiece of the program is a study enrolling active duty volunteers from the Air Force Medical Service to evaluate the utility of their genomic information and its effect on their personalized care and on their behavior. The data, evidence, and infrastructure developed in the PC2-Z program are also planned to be implemented by the sister services.

引用

页码：333 / 344

页数：12