Palladium-Catalyzed Cross-Coupling Reactions of Benzyl Indium Reagents with Aryl Iodides

被引：42
|
作者：
Chupak, Louis S. [1 ]
Wolkowski, Joanna P. [1 ]
Chantigny, Yves A. [1 ]
机构：
[1] Pfizer Inc, Groton Labs, Groton, CT 06340 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 03期
关键词：
ARYLBORONIC ACIDS; HALIDES; DIARYLMETHANES; ORGANOMETALLICS; ALKYLATION; HETEROARYL; CHLORIDES; PARTNERS; METAL;
D O I：
10.1021/jo802280m
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein described is an operationally simple procedure for generating benzyl indium species from readily available benzyl bromides and indium metal followed by in situ palladium-catalyzed coupling with aryl halides. The procedure provides diarylmethanes in modest to excellent yield and tolerates a variety of functional groups in both coupling partners.
引用
收藏
页码：1388 / 1390
页数：3
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