Medications for Substance Use Disorders

被引:38
|
作者
Douaihy, Antoine B. [1 ]
Kelly, Thomas M. [2 ]
Sullivan, Carl [3 ]
机构
[1] Univ Pittsburgh, Dept Psychiat, Western Psychiat Inst & Clin, Sch Med, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Ctr Psychiat & Chem Dependency Serv, Med Ctr, Pittsburgh, PA 15213 USA
[3] W Virginia Univ, Addict Program, Morgantown, WV 26506 USA
关键词
Substance use disorders; detoxification; relapse prevention; nicotine; alcohol; opioids; social workers; SUSTAINED-RELEASE BUPROPION; PLACEBO-CONTROLLED TRIAL; RECEPTOR PARTIAL AGONIST; ALCOHOL-DEPENDENCE; SMOKING-CESSATION; DOUBLE-BLIND; NALTREXONE; EFFICACY; PHARMACOTHERAPY; DISULFIRAM;
D O I
10.1080/19371918.2013.759031
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In this article, the authors briefly review the pharmacotherapeutic agents that are currently available for the treatment of substance use disorders. Nicotine replacement therapies are most effective for tobacco cessation. Naltrexone, acamprosate, and disulfiram are effective for reducing alcohol use. The most effective pharmacotherapies for opiate use disorders are agonist therapies, including methadone and buprenorphine. The authors also examine recent advances in medication development for other substance use disorders such as stimulant addiction. The role of medication adherence and behavioral treatments and the integration of behavioral and pharmacotherapeutic interventions are also discussed.
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页码:264 / 278
页数:15
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