The synthesis of triterpene 2-deoxy-alpha-D-hexopyranosides from glycals and their effect on reparative processes

被引：0

作者：

Baltina, LA ^{[1
]}

Flekhter, OB ^{[1
]}

Vasileva, EV ^{[1
]}

Davydova, VA ^{[1
]}

Ismagilova, AF ^{[1
]}

Zarudii, FS ^{[1
]}

Tolstikov, GA ^{[1
]}

机构：

[1] RUSSIAN ACAD SCI,INST ORGAN CHEM,UFA SCI CTR,UFA 450054,RUSSIA

来源：

BIOORGANICHESKAYA KHIMIYA | 1997年 / 23卷 / 06期

关键词：

triterpene; 2-deoxy-alpha-D-hexopyranosides; synthesis; di(sym-collidine)iodonium perchlorate; antiulcer activity; reparative skin regeneration;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Triterpene 2-deoxy-alpha-D-hexopyranosides were synthesized by the glycosylation of oleanane triterpene alcohols with D-glucal and D-galactal acetates in the presence of di(sym-collidine)iodonium perchlorate with subsequent deiodination and deacetylation of the resulting 2-deoxy-2-iodo-alpha-D-glycosides. 2-Deoxy-alpha-D-arabino- and -lyxo-hexopyranosides of methyl glycyrrhetinate demonstrated pronounced antiulcer activity and stimulated reparative skin regeneration in rats more effectively than glycyrrhizic acid and methyluracil.

引用

页码：512 / 518

页数：7

共 50 条

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