Pneumocystis pneumonia in HIV-1-infected patients

被引：18

作者：

Shibata, Satoshi ^{[1
]}

Kikuchi, Toshiaki ^{[2
]}

机构：

[1] Niigata City Gen Hosp, Dept Resp Med, Niigata 9501197, Japan

[2] Niigata Univ, Grad Sch Med & Dent Sci, Dept Resp Med & Infect Dis, Chuo Ku, 1-757 Asahimachidori, Niigata 9518510, Japan

来源：

RESPIRATORY INVESTIGATION | 2019年 / 57卷 / 03期

基金：

日本学术振兴会;

关键词：

Pneumocystis pneumonia; Acquired immunodeficiency syndrome; Human immunodeficiency virus; Opportunistic infection; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; BETA-D-GLUCAN; CARINII-PNEUMONIA; TRIMETHOPRIM-SULFAMETHOXAZOLE; RANDOMIZED-TRIAL; AEROSOLIZED PENTAMIDINE; PRIMARY PROPHYLAXIS; JIROVECII PNEUMONIA; DOUBLE-BLIND; AIDS;

D O I：

10.1016/j.resinv.2019.01.009

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Pneumocystis pneumonia (PCP) is an opportunistic disease that mainly affects patients with a deficiency of cell-mediated immunity, especially acquired immunodeficiency syndrome (AIDS). The incidence of PCP in these patients has declined substantially owing to the widespread use of antiretroviral therapy and PCP prophylaxis. However, PCP is still a major AIDS-related opportunistic infection, particularly in patients with advanced immunosuppression in whom human immunodeficiency virus type 1 (HIV-1) infection remains undiagnosed or untreated. The clinical manifestations, diagnosis, treatment, and prevention of PCP in patients with HIV-1 infection are addressed in this review. (C) 2019 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

引用

页码：213 / 219

页数：7

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