DDQ-mediated direct Cross-Dehydrogenative-Coupling (CDC) between benzyl ethers and simple ketones

被引：383
|
作者：
Zhang, YH
Li, CJ [1 ]
机构：
[1] Tulane Univ, Dept Chem, New Orleans, LA 70118 USA
[2] McGill Univ, Dept Chem, Montreal, PQ H3A 2K6, Canada
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 13期
关键词：
D O I：
10.1021/ja060050p
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A direct Cross-Dehydrogenative-Coupling (CDC) between benzyl ethers and simple ketones was developed without using any metal catalyst. By using DDQ, various benzyl ethers and simples ketones were coupled together directly to form β-alkoxyl ketones efficiently. A mechanism in which the DDQ serves the double roles of an oxidizing agent and an organomediator was proposed. Copyright © 2006 American Chemical Society.
引用
收藏
页码：4242 / 4243
页数：2
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