Pediatric trauma-related coagulopathy: Balanced resuscitation, goal-directed therapy and viscoelastic assays

被引：12

作者：

Drucker, Natalie A. ^{[1
]}

Wang, S. Keisin ^{[1
]}

Newton, Christopher ^{[2
]}

机构：

[1] Riley Hosp Children, Pediat Surg Sect, Dept Surg, Indianapolis, IN USA

[2] Childrens Hosp Oakland, Dept Surg, Oakland, CA USA

来源：

SEMINARS IN PEDIATRIC SURGERY | 2019年 / 28卷 / 01期

关键词：

Trauma-induced coagulopathy; Thromboelastography; Damage control resuscitation; Tranexamic acid; DAMAGE-CONTROL RESUSCITATION; FROZEN LIQUID PLASMA; TRANEXAMIC ACID; MASSIVE TRANSFUSION; IMPROVED SURVIVAL; INJURED CHILDREN; MORTALITY; BLOOD; ADMISSION; IMPACT;

D O I：

10.1053/j.sempedsurg.2019.01.011

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The improved understanding of trauma-induced coagulopathy in adults has led to an evolution in the strategies of damage-control resuscitation. While its impact on the care of pediatric trauma patients is of tremendous interest, the evidence is sparse, and a great deal of research is still needed in this domain. Areas of particular interest include age-related differences in hemostasis and balanced resuscitation, advances in functional coagulation assays and effective adjunctive medications, such as tranexamic acid, for hemorrhage control. This review examines the available pediatric data, reviews applicable adult data, and introduces areas of investigation that will impact pediatric trauma care in the future. (C) 2019 Elsevier Inc. All rights reserved.

引用

页码：61 / 66

页数：6

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