SYMMETRY-BREAKING BIFURCATIONS FOR FREE BOUNDARY PROBLEMS MODELING TUMOR GROWTH

被引:2
|
作者
Pan, Hongjing [1 ]
Xing, Ruixiang [2 ]
机构
[1] South China Normal Univ, Sch Math Sci, Guangzhou 510631, Peoples R China
[2] Sun Yat Sen Univ, Sch Math, Guangzhou 510275, Peoples R China
关键词
Local bifurcation; non-axisymmetric solution; tumor growth; Stokes equation; spherical harmonics; CARCINOMA IN-SITU; STATIONARY SOLUTIONS; MATHEMATICAL-MODEL; INSTABILITY; STABILITY;
D O I
10.12775/TMNA.2021.064
中图分类号
O1 [数学];
学科分类号
0701 ; 070101 ;
摘要
We study a classic free boundary problem modeling solid tumor growth. The problem contains a parameter mu. It is well known that the problem admit a unique radially symmetric solution with free boundary r = R-S and a sequence of symmetry-breaking branches of axisymmetric solutions bifurcating from the spherical state r = R-S at an increasing sequence of mu = mu(l)(R-S) (l >= 2 even) with free boundary r = R-S + epsilon Y-l,Y-0(theta) + O(epsilon(2)), where Y-l,Y-0 is the spherical harmonic of mode (l,0). In this paper, we use group-theoretic ideas to obtain a plethora of new branches of non-axisymmetric solutions bifurcating at mu = mu(l)(R-S) (l >= 2). New solutions can model more complex shapes of tumor tissues than the known axisymmetric solutions. The approach is also applicable to many other free boundary problems arising in tumor growth, including a model involving fluid-like tissue.
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页码:387 / 412
页数:26
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