MBGD update 2013: the microbial genome database for exploring the diversity of microbial world

被引：32
|
作者：
Uchiyama, Ikuo [1 ,2 ]
Mihara, Motohiro [3 ]
Nishide, Hiroyo [2 ]
Chiba, Hirokazu [1 ]
机构：
[1] Natl Inst Nat Sci, Natl Inst Basic Biol, Lab Genome Informat, Okazaki, Aichi 4448585, Japan
[2] Natl Inst Nat Sci, Natl Inst Basic Biol, Data Integrat & Anal Facil, Okazaki, Aichi 4448585, Japan
[3] Dynacom Co Ltd, Kobe Incubat Off 202, Chuo Ku, Kobe, Hyogo 6500045, Japan
来源：
NUCLEIC ACIDS RESEARCH | 2013年 / 41卷 / D1期
基金：
日本学术振兴会;
关键词：
GENES;
D O I：
10.1093/nar/gks1006
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The microbial genome database for comparative analysis (MBGD, available at http://mbgd.genome.ad.jp/) is a platform for microbial genome comparison based on orthology analysis. As its unique feature, MBGD allows users to conduct orthology analysis among any specified set of organisms; this flexibility allows MBGD to adapt to a variety of microbial genomic study. Reflecting the huge diversity of microbial world, the number of microbial genome projects now becomes several thousands. To efficiently explore the diversity of the entire microbial genomic data, MBGD now provides summary pages for pre-calculated ortholog tables among various taxonomic groups. For some closely related taxa, MBGD also provides the conserved synteny information (core genome alignment) pre-calculated using the CoreAligner program. In addition, efficient incremental updating procedure can create extended ortholog table by adding additional genomes to the default ortholog table generated from the representative set of genomes. Combining with the functionalities of the dynamic orthology calculation of any specified set of organisms, MBGD is an efficient and flexible tool for exploring the microbial genome diversity.
引用
收藏
页码：D631 / D635
页数：5
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