ALZHEIMER'S DISEASE JNK3 as new target in AD?

被引：4
|
作者：
Flemming, Alexandra
机构：
来源：
NATURE REVIEWS DRUG DISCOVERY | 2012年 / 11卷 / 11期
关键词：
D O I：
10.1038/nrd3876
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：829 / 829
页数：1
相关论文
共 50 条
  • [1] JNK3 as new target in AD?
    Alexandra Flemming
    Nature Reviews Drug Discovery, 2012, 11 : 829 - 829
  • [2] INCREASED ACTIVATION OF JNK3 IN ALZHEIMER'S DISEASE
    Solas, M.
    Kohoutova, L.
    Ramirez, M. J.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2014, 115 : 43 - 43
  • [3] Recent advances of small molecule JNK3 inhibitors for Alzheimer?s disease
    Qin, Pengxia
    Ran, Yingying
    Liu, Yujing
    Wei, Chao
    Luan, Xiaoyi
    Niu, Haoqian
    Peng, Jie
    Sun, Jie
    Wu, Jingde
    BIOORGANIC CHEMISTRY, 2022, 128
  • [4] In silico Docking Studies and Potential Lead Identification against JNK3 for Alzheimer's Disease
    Singh, Nishtha
    Upadhyay, Sonal
    Jaiswar, Ankur
    Mishra, Nidhi
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION, 2019, 9 (04) : 220 - 222
  • [5] JNK3 as a Therapeutic Target for Neurodegenerative Diseases
    Antoniou, Xanthi
    Falconi, Mattia
    Di Marino, Daniele
    Borsello, Tiziana
    JOURNAL OF ALZHEIMERS DISEASE, 2011, 24 (04) : 633 - 642
  • [6] Discovery of novel imidazole chemotypes as isoform-selective JNK3 inhibitors for the treatment of Alzheimer's disease
    Jun, Joonhong
    Yang, Songyi
    Lee, Junghun
    Moon, Hyungwoo
    Kim, Jinwoong
    Jung, Hoyong
    Im, Daseul
    Oh, Youri
    Jang, Miyoung
    Cho, Hyunwook
    Baek, Jihyun
    Kim, Hyejin
    Kang, Dahyun
    Bae, Hyunah
    Tak, Chanwool
    Hwang, Kyungrim
    Kwon, Hoseok
    Kim, HyunTae
    Hah, Jung-Mi
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 245
  • [7] Carbamate JNK3 Inhibitors Show Promise as Effective Treatments for Alzheimer?s Disease: In Vivo Studies on Mouse Models
    Jun, Joonhong
    Moon, Hyungwoo
    Yang, Songyi
    Lee, Junghun
    Baek, Jihyun
    Kim, Hyejin
    Cho, Hyunwook
    Hwang, Kyungrim
    Ahn, Soyeon
    Kim, Yuro
    Kim, Gibeom
    Kim, HyunTae
    Kwon, Hoseok
    Hah, Jung-Mi
    JOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (09) : 6372 - 6390
  • [8] Targeting JNK3 for Alzheimer's disease: Design and synthesis of novel inhibitors with aryl group diversity utilizing wide pocket
    Kim, Hyejin
    Park, Haebeen
    Jun, Joonhong
    Moon, Jihyun
    Oh, Jooyoung
    Bhujbal, Swapnil P.
    Hah, Jung-Mi
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 285
  • [9] Photobiomodulation suppresses JNK3 by activation of ERK/MKP7 to attenuate AMPA receptor endocytosis in Alzheimer's disease
    Shen, Qi
    Liu, Lei
    Gu, Xiaotong
    Xing, Da
    AGING CELL, 2021, 20 (01)
  • [10] New insights into the structural dynamics of the kinase JNK3
    Pankaj Mishra
    Stefan Günther
    Scientific Reports, 8
12345