Humoral immune response to the respiratory syncytial virus (RSV) in adult patients with chronic obstructive bronchitis and persistent RSV antigens

被引：0
|
作者：
Krivitskaya, VZ
Yakovleva, NV
Alexandrova, NI
机构：
来源：
VOPROSY VIRUSOLOGII | 1996年 / 41卷 / 05期
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中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Specific humoral immune response has been studied in 8 patients with chronic obstructive bronchitis, in whom the persistence of RSV was detected, and in a group of patients without RSV persistence. Humoral immunity in patients with RSV persistence vs. those with acute and chronic bronchitis without viral persistence was characterized by the following features: a) earlier and more active production of IgG and, even more so, IgM and IgA; b) long persistence of high titers of anti-RSV IgG, IgM, and IgA - up to 17, 28, and 30 weeks, respectively; c) low anti-RSV neutralizing activity of serum antibodies.
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页码：234 / 237
页数：4
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