Thiopurine Metabolite, 6-Thioguanine Nucleotide, Correlates with Detection of Antibodies Against Infliximab in Patients with Inflammatory Bowel Disease

被引:0
|
作者
Mogensen, Ditte [1 ]
Brynskov, Jorn [1 ]
Ainsworth, Mark [1 ]
Nersting, Jacob [2 ]
Schmiegelow, Kjeld [2 ]
Steenholdt, Casper [1 ]
机构
[1] Univ Copenhagen, Herlev Hosp, Dept Gastroenterol, Herlev, Denmark
[2] Univ Copenhagen Hosp, Rigshosp, Pediat Oncol Res Lab, Copenhagen, Denmark
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
P-116
引用
收藏
页码:S41 / S42
页数:2
相关论文
共 50 条
  • [1] Association between 6-thioguanine nucleotide levels and preventing production of antibodies to infliximab in patients with inflammatory bowel disease
    Phillips, Jennifer
    Leary, Sam
    Tyrrell-Price, Jonathan
    BMJ OPEN GASTROENTEROLOGY, 2023, 10 (01):
  • [2] Assessment of 6-thioguanine nucleotide metabolite level in inflammatory bowel disease patients treated with azathioprine
    Pavlovska, K.
    Miceska, M. Slaninka
    Mishevska, P.
    Ribarska, J. Tonic
    Atanasovska, E.
    Kikerkov, I.
    Efremovska, L.
    Petrushevska, M.
    JOURNAL OF CROHNS & COLITIS, 2016, 10 : S371 - S371
  • [3] High Thiopurine Methyltransferase Activity Does Not Affect Concentration of Azathioprine Metabolite 6-Thioguanine Nucleotide in Inflammatory Bowel Disease
    Jonason, David
    Sievers, Tyson
    Abraham, James M.
    Vaughn, Byron
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2019, 114 : S461 - S462
  • [4] Relationship Between Thiopurine S-Methyltransferase Genotype/Phenotype and 6-Thioguanine Nucleotide Levels in 316 Patients With Inflammatory Bowel Disease on 6-Thioguanine
    Bayoumy, Ahmed B.
    Mulder, Chris J. J.
    Loganayagam, Aathavan
    Sanderson, Jeremy D.
    Anderson, Simon
    Boekema, Paul J.
    Derijks, Luc J. J.
    Ansari, Azhar R.
    THERAPEUTIC DRUG MONITORING, 2021, 43 (05) : 617 - 623
  • [5] The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease
    Goldenberg, BA
    Rawsthorne, P
    Bernstein, CN
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2004, 99 (09): : 1744 - 1748
  • [6] 6-Thioguanine nucleotide levels are associated with infliximab but not adalimumab levels in inflammatory bowel disease patients on combination therapy
    Yu, Natalie
    Lee, Tanya
    Tassone, Daniel
    Vogrin, Sara
    Phan, Steven
    Wu, Damien M.
    Zhang, Jason
    Wang, Luke
    Tjahyadi, Jason
    Dutt, Krishneel
    Liou, Hana
    Basnayake, Chamara
    Wright, Emily
    Niewiadomski, Ola
    Lust, Mark
    Schulberg, Julien
    Kamm, Michael A.
    Connell, William
    Thompson, Alexander J.
    Hilmi, Ida
    Ali, Raja A. Raja
    Wei, Shu C.
    De Cruz, Peter
    Friedman, Antony B.
    Moore, Gregory T.
    Van Langenberg, Daniel
    Ding, Nik S.
    INTERNAL MEDICINE JOURNAL, 2024, 54 (11) : 1856 - 1866
  • [7] Concentrations of 6-Thioguanine Nucleotide Correlate With Trough Levels of Infliximab in Patients With Inflammatory Bowel Disease on Combination Therapy
    Yarur, Andres J.
    Kubiliun, Maddie J.
    Czul, Frank
    Sussman, Daniel A.
    Quintero, Maria A.
    Jain, Anjali
    Drake, Katherine A.
    Hauenstein, Scott I.
    Lockton, Steven
    Deshpande, Amar R.
    Barkin, Jamie S.
    Singh, Sharat
    Abreu, Maria T.
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2015, 13 (06) : 1118 - +
  • [8] Monitoring 6-thioguanine nucleotide concentrations in Japanese patients with inflammatory bowel disease
    Andoh, Akira
    Tsujikawa, Tomoyuki
    Ban, Hiromitsu
    Hashimoto, Takayoshi
    Bamba, Shigeki
    Ogawa, Atsuhiro
    Sasaki, Masaya
    Saito, Yasuharu
    Fujiyama, Yoshihide
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2008, 23 (09) : 1373 - 1377
  • [9] Thiopurine methyltransferase activity combined with 6-thioguanine metabolite levels predicts clinical response to thiopurines in patients with inflammatory bowel disease
    Kwan, L. Y.
    Devlin, S. M.
    Mirocha, J. M.
    Papadakis, K. A.
    DIGESTIVE AND LIVER DISEASE, 2008, 40 (06) : 425 - 432
  • [10] Pharmacokinetics of 6-thioguanine in patients with inflammatory bowel disease
    Derijks, LJJ
    Gilissen, LPL
    Engels, LGJB
    Bos, LP
    Bus, PJ
    Lohman, JJHM
    van Deventer, SJH
    Hommes, DW
    Hooymans, PM
    THERAPEUTIC DRUG MONITORING, 2006, 28 (01) : 45 - 50