Effect of macitentan on morbidity and mortality in pulmonary arterial hypertension: A randomised controlled trial (SERAPHIN)

被引：0

作者：

Ghofrani, Hossein-Ardeschir ^{[1
]}

Channick, Richard ^{[2
]}

Delcroix, Marion ^{[3
]}

Galie, Nazzareno ^{[4
]}

Jansa, Pavel ^{[5
]}

Le Brun, Franck-Olivier ^{[6
]}

Mehta, Sanjay ^{[7
]}

Mittelholzer, Camilla ^{[6
]}

Pulido, Tomas ^{[8
]}

Sastry, B. K. S. ^{[9
]}

Sitbon, Olivier ^{[10
]}

Souza, Rogerio ^{[11
]}

Torbicki, Adam ^{[12
]}

Rubin, Lewis ^{[13
]}

Simonneau, Gerald ^{[10
]}

机构：

[1] Univ Hosp Giessen, Dept Internal Med 2, Pulm Hypertens Div, Giessen, Germany

[2] Massachusetts Gen Hosp, Pulm & Crit Care, Boston, MA 02114 USA

[3] Univ Hosp Gasthuisberg, Dept Pneumol, Leuven, Belgium

[4] Univ Bologna, Inst Cardiol, Bologna, Italy

[5] Charles Univ Prague, Clin Dept Cardiol & Angiol, Fac Med 1, Dept Med 2, Prague, Czech Republic

[6] Actel Pharmaceut Ltd, Allschwil, Switzerland

[7] Univ Western Ontario, Dept Med, Div Respirol, London Hlth Sci Ctr, London, ON, Canada

[8] Natl Inst Cardiol, Cardiopulm Dept, Mexico City, DF, Mexico

[9] CARE Hosp, Dept Cardiol, Hyderabad, Andhra Pradesh, India

[10] Univ Paris 11, CHU Bicetre, Le Kremlin Bicetre, France

[11] Univ Sao Paulo, Sch Med, Inst Heart, Dept Pulm, Sao Paulo, Brazil

[12] ECZ Otwock, Dept Pulm Circulat & Thromboembol Dis, Ctr Postgrad Med Educ, Otwock, Poland

[13] Univ Calif San Diego, Div Pulm & Crit Care Med, San Diego, CA 92103 USA

来源：

EUROPEAN RESPIRATORY JOURNAL | 2013年 / 42卷

关键词：

Pulmonary hypertension; Treatments;

D O I：

暂无

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

2443

引用

页数：2

共 50 条

[1] Effect of macitentan on haemodynamics in SERAPHIN, a randomised controlled trial in pulmonary arterial hypertension (PAH)
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Delcroix, Marion
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Ghofrani, Hossein-Ardeschir
Jansa, Pavel
Le Brun, Franck-Olivier
Mehta, Sanjay
Perchenet, Loic
Pulido, Tomas
Sastry, B. K. S.
Souza, Rogerio
Torbicki, Adam
Rubin, Lewis
Simonneau, Gerald
[J]. EUROPEAN RESPIRATORY JOURNAL, 2013, 42
[2] EFFECT OF MACITENTAN ON PULMONARY ARTERIAL HYPERTENSION-RELATED HOSPITALISATIONS: RESULTS FROM THE RANDOMISED CONTROLLED SERAPHIN TRIAL
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[J]. THORAX, 2013, 68 : A143 - A143
[3] Macitentan and Morbidity and Mortality in Pulmonary Arterial Hypertension
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[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (09): : 809 - 818
[4] Macitentan in Pulmonary Arterial Hypertension: A Focus on Combination Therapy in the SERAPHIN Trial
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[J]. AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS, 2018, 18 (01) : 1 - 11
[5] Macitentan in Pulmonary Arterial Hypertension: A Focus on Combination Therapy in the SERAPHIN Trial
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[J]. American Journal of Cardiovascular Drugs, 2018, 18 : 1 - 11
[6] EFFECT OF MACITENTAN ON HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN PULMONARY ARTERIAL HYPERTENSION (PAH): RESULTS FROM THE SERAPHIN RANDOMISED CONTROLLED TRIAL
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[J]. INTERNAL MEDICINE JOURNAL, 2014, 44 : 31 - 31
[7] EFFECT OF MACITENTAN ON HAEMODYNAMICS IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION: RESULTS FROM THE LONG-TERM, RANDOMISED, PLACEBO-CONTROLLED SERAPHIN TRIAL
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[8] REDUCTION OF PULMONARY ARTERIAL HYPERTENSION (PAH)-RELATED HOSPITALIZATIONS WITH MACITENTAN IN THE RANDOMIZED CONTROLLED TRIAL SERAPHIN
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[J]. EUROPEAN HEART JOURNAL, 2013, 34 : 186 - 186
[10] Macitentan reduces the risk of morbidity and mortality irrespective of the presence or absence of right ventricular (RV) impairment: Results from the randomised SERAPHIN trial in pulmonary arterial hypertension (PAH)
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