Inhibition of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and FK506 in a pancreatic β-cell line and in primary mature pancreatic islets of transgenic mice

被引：0

作者：

Oetjen, E ^{[1
]}

Grapentin, D ^{[1
]}

Baun, D ^{[1
]}

Blume, R ^{[1
]}

Krause, D ^{[1
]}

Beimesche, S ^{[1
]}

Cierny, I ^{[1
]}

Knepel, W ^{[1
]}

机构：

[1] Univ Gottingen, Dept Mol Pharmacol, D-37075 Gottingen, Germany

来源：

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY | 2002年 / 365卷

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

270

引用

页码：R71 / R71

页数：1

共 12 条

[1] Inhibition of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus in primary, mature islets of transgenic mice
Oetjen, E
Baun, D
Beimesche, S
Krause, D
Cierny, I
Blume, R
Dickel, C
Wehner, S
Knepel, W
MOLECULAR PHARMACOLOGY, 2003, 63 (06) : 1289 - 1295
[2] Inhibition of the transcription factor NFATp by the immunosuppressive drugs cyclosporin A and FK506 in nonimmune cells
Fürstenau, U
Schwaninger, M
Blume, R
Jendrusch, EM
Knepel, W
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1998, 358 (01) : R672 - R672
[3] Inhibition of CREB/CRE-directed transcription by the immunosuppressive drugs cyclosporin A and FK506 depends on the promoter context
Knepel, W
Siemann, G
Blume, R
Oetjen, E
Chilla, M
Schwaninger, M
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1998, 357 (04) : R17 - R17
[4] Inhibition of CREB/CRE-mediated transcription by the immunosuppressive drugs cyclosporin A and FK506 depends on the promoter context
Siemann, G
Blume, R
Oetjen, E
Schwaninger, M
Knepel, W
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1998, 358 (01) : R155 - R155
[5] Inhibition of CREB- and cAMP response element-mediated gene transcription by the immunosuppressive drugs cyclosporin A and FK506 in T cells
Kruger, M
Schwaninger, M
Blume, R
Oetjen, E
Knepel, W
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1997, 356 (04) : 433 - 440
[6] Inhibition of CREB- and cAMP response element-mediated gene transcription by the immunosuppressive drugs cyclosporin A and FK506 in T cells
Meike Krüger
M. Schwaninger
Roland Blume
Elke Oetjen
W. Knepel
Naunyn-Schmiedeberg's Archives of Pharmacology, 1997, 356 : 433 - 440
[7] TRANSCRIPTIONAL INHIBITION OF INSULIN BY FK506 AND POSSIBLE INVOLVEMENT OF FK506 BINDING PROTEIN-12 IN PANCREATIC BETA-CELL
TAMURA, K
FUJIMURA, T
TSUTSUMI, T
NAKAMURA, K
OGAWA, T
ATUMARU, C
HIRANO, Y
OHARA, K
OHTSUKA, K
SHIMOMURA, K
KOBAYASHI, M
TRANSPLANTATION, 1995, 59 (11) : 1606 - 1613
[8] Inhibition of cyclic AMP response element-binding protein cyclic AMP response element-mediated transcription by the immunosuppressive drugs cyclosporin A and FK506 depends on the promoter context
Siemann, G
Blume, R
Grapentin, D
Oetjen, E
Schwaninger, M
Knepel, W
MOLECULAR PHARMACOLOGY, 1999, 55 (06) : 1094 - 1100
[9] THE IMMUNOSUPPRESSIVE DRUGS CYCLOSPORINE-A AND FK506 INHIBIT CALCINEURIN PHOSPHATASE-ACTIVITY AND GENE-TRANSCRIPTION MEDIATED THROUGH THE CAMP-RESPONSIVE ELEMENT IN A NONIMMUNE CELL-LINE
SCHWANINGER, M
BLUME, R
OETJEN, E
KNEPEL, W
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1993, 348 (05) : 541 - 545
[10] SIMULTANEOUS ACTIVATION BY INSULIN AND GLUCOCORTICOID IS REQUIRED FOR AMYLASE GENE-EXPRESSION IN 266 PANCREATIC ACINAR CELL-LINE OF TRANSGENIC MICE
FENG, HW
OWYANG, C
GASTROENTEROLOGY, 1993, 104 (04) : A303 - A303

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