In situ generation of hydroperoxide by oxidation of benzhydrols to benzophenones using sodium hydride under oxygen atmosphere: use for the oxidative cleavage of cyclic 1,2-diketones to dicarboxylic acids

被引：13

作者：

Kang, Sunhae ^{[1
]}

Lee, Soyoung ^{[1
]}

Jeon, Minju ^{[1
]}

Kim, Sun Min ^{[2
]}

Kim, Young Sug ^{[2
]}

Han, Hogyu ^{[1
]}

Yang, Jung Woon ^{[2
]}

机构：

[1] Korea Univ, Dept Chem, Seoul 136701, South Korea

[2] Sungkyunkwan Univ, Dept Energy Sci, Suwon 440746, South Korea

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 05期

关键词：

Oxidative cleavage; Cyclic 1,2-diketone; Dicarboxylic acid; Sodium hydride; Benzhydrol; MAIN-GROUP ELEMENTS; CIS-DIHYDROXYLATION; HYDROGEN-PEROXIDE; TRANSITION-METALS; FACILE SYNTHESIS; MULTIPLE BONDS; ALKENES; MECHANISM; ALDEHYDES; DERIVATIVES;

D O I：

10.1016/j.tetlet.2012.10.127

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile oxidative cleavage of cyclic 1,2-diketones 1 to dicarboxylic acids 3 with hydroperoxide generated in situ has been developed. In situ generation of hydroperoxide was effected by the oxidation of 4,4'-dichlorobenzhydrol 2f to 4,4'-dichlorobenzophenone 41 using sodium hydride under oxygen atmosphere. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：373 / 376

页数：4