Subacute toxicity study of CKD-501, a novel thiazolidinedione, after 4-week repeated oral administration in mice

被引:0
|
作者
Moon, Kyoung-Sik [1 ]
Noh, Jung-Ho [1 ]
Kim, Yong-Bum [1 ]
Jeong, Eun Ju [1 ]
Hwang, In-Chang [2 ]
Kim, Dal-Hyun [2 ]
Yu, Ho-Sung [2 ]
Yun, Hyo-In [3 ]
机构
[1] Korea Inst Toxicol, Taejon, South Korea
[2] Chong Kun Dang Pharmaceut Corp, CKD Res Inst, Yongin, South Korea
[3] Chungnam Natl Univ, Coll Vet Med, Taejon, South Korea
关键词
D O I
10.1016/j.toxlet.2013.05.637
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
引用
收藏
页码:S255 / S255
页数:1
相关论文
共 50 条
  • [1] Subacute toxicity and toxicokinetics of a new antibiotic, DW-224a, after single and 4-week repeated oral administration in dogs
    Han, JH
    Kim, JC
    Chung, MK
    Kim, B
    Choi, DR
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2003, 26 (06) : 832 - 839
  • [2] Subacute toxicity and toxicokinetics of CJ-10882, a type IV phosphodiesterase inhibitor, after 4-week repeated oral administration in dogs
    Han, J
    Shin, HC
    Kim, JC
    Kim, B
    FOOD AND CHEMICAL TOXICOLOGY, 2004, 42 (03) : 373 - 380
  • [3] A 4-week Repeated Dose Toxicity Study of Glycine in Rats by Gavage Administration
    Shibui, Yusuke
    Miwa, Tadashi
    Yamashita, Mayumi
    Chin, Keigi
    Kodama, Terutaka
    JOURNAL OF TOXICOLOGIC PATHOLOGY, 2013, 26 (04) : 405 - 412
  • [4] Subacute toxicities and toxicokinetics of a new erectogenic, DA-8159, after single and 4-week repeated oral administration in dogs
    Shim, SH
    Lee, EJ
    Kim, JH
    Kim, SH
    Kwon, JW
    Kim, WB
    Cha, SW
    Lee, MG
    BIOPHARMACEUTICS & DRUG DISPOSITION, 2001, 22 (03) : 109 - 117
  • [5] CKD-501, a novel selective PPAR. agonist, shows no carcinogenic potential in ICR mice following oral administration for 104 weeks
    Moon, Kyoung-Sik
    Lee, Ji-Eun
    Lee, Hee Su
    Hwang, In-Chang
    Kim, Dal-Hyun
    Park, Hyun-Kyu
    Choi, Hyun-Ji
    Jo, Woori
    Son, Woo-Chan
    Yun, Hyo-In
    JOURNAL OF APPLIED TOXICOLOGY, 2014, 34 (12) : 1271 - 1284
  • [6] Pharmacokinetics and safety of CKD-501, a novel PPAR alpha/gamma dual agonist, after oral administration in healthy female subjects.
    Lee, H. E.
    Kim, J. W.
    Kim, J. R.
    Lim, K. S.
    Kim, B. H.
    Ahn, S. K.
    Kim, C.
    Yu, K. S.
    Shin, S. G.
    Jang, I. J.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 83 : S95 - S95
  • [7] Histopathological Evaluation of Heart Toxicity of a Novel Selective PPAR-γ Agonists CKD-501 in db/db Mice
    Yang, Hyun-Il
    Kim, Woo Sik
    Kim, Dal-Hyun
    Kang, Jin Seok
    BIOMOLECULES & THERAPEUTICS, 2013, 21 (01) : 84 - 88
  • [8] A 4-WEEK ORAL TOXICITY STUDY WITH ACETALDEHYDE AND FORMALDEHYDE IN RATS
    TIL, HP
    WOUTERSEN, RA
    FERON, VJ
    CLARY, JJ
    PHARMACEUTISCH WEEKBLAD-SCIENTIFIC EDITION, 1987, 9 (01) : 43 - 43
  • [9] Subacute toxicities and toxicokinetics of DA-8159, a new phosphodiesterase type V inhibitor, after single and 4-week repeated oral administration in rats
    Shim, HJ
    Kim, YC
    Jang, JM
    Park, KJ
    Kim, DH
    Kang, KK
    Ahn, BO
    Kwon, JW
    Kim, WB
    Lee, MG
    BIOPHARMACEUTICS & DRUG DISPOSITION, 2003, 24 (09) : 409 - 418
  • [10] A 4-week repeated oral dose toxicity study of the methanol extract from Diospyros canaliculata in rats
    Dzoyem J.P.
    Nkegoum B.
    Kuete V.
    Comparative Clinical Pathology, 2013, 22 (1) : 75 - 81