Treatment of Central Precocious Puberty Using Gonadotropin-releasing Hormone Agonists

被引：1
|
作者：
Cafasso, Mandi [1 ]
Elder, Deborah A. [2 ]
Blum, Samantha [3 ]
Weis, Tammy [3 ]
Hornung, Lindsey [4 ]
Khoury, Jane C. [4 ]
Stenger, Peggy J. [2 ]
Rose, Susan R. [2 ]
机构：
[1] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA
[2] Cincinnati Childrens Hosp Med Ctr, Dept Pediat, Div Endocrinol, Cincinnati, OH 45229 USA
[3] Cincinnati Childrens Hosp Med Ctr, Div Endocrinol, Cincinnati, OH 45229 USA
[4] Cincinnati Childrens Hosp Med Ctr, Div Biostat & Epidemiol, Cincinnati, OH 45229 USA
来源：
JNP-JOURNAL FOR NURSE PRACTITIONERS | 2015年 / 11卷 / 07期
关键词：
GnRHa therapy; pediatrics; precocious puberty short stature; TRIPTORELIN; 11.25; MG; LEUPROLIDE ACETATE; DEPOT; EFFICACY; CHILDREN; GIRLS;
D O I：
10.1016/j.nurpra.2015.05.001
中图分类号：
R47 [护理学];
学科分类号：
1011 ;
摘要：
Precocious puberty is treated with gonadotropin-releasing :hormone agonists (GnRHa). In, this study we describe our clinical experience with pubertal suppression. from GnRHa, using monthly and 3-monthly formulations. A retrospective Chart review for the period between 2006 and 2010 was done for 64 patients who were undergoing treatment for central precocious puberty. Two treatment cohorts were observed for 2+ years. Pubertal suppression was inadequate for 14 of 38 children (37%) on GnRHa given Monthly and for 2 of 26 (8%) children given GnRHa every 3 Months. Based on our findings Of adequate pubertal suppression, decreased frequency of injections, and fewer facility visits, We consider GnRHa 5-monthly injection to be therapy
引用
收藏
页码：686 / 694
页数：9
相关论文
共 50 条
  • [1] The clinical effects of gonadotropin-releasing hormone agonists for the treatment of children patients with central precocious puberty
    Xue, Y.
    Wang, P.
    Wang, S-Q
    Gao, Y-Q
    [J]. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2018, 22 (15) : 5014 - 5017
  • [2] TREATMENT OF CENTRAL PRECOCIOUS PUBERTY USING GONADOTROPIN-RELEASING-HORMONE (GNRH) AGONISTS
    SIZONENKO, PC
    VILCHEZ, O
    THEINTZ, G
    NUSSLE, D
    BISCHOF, P
    [J]. HELVETICA PAEDIATRICA ACTA, 1987, 42 (01) : 70 - 70
  • [3] GONADOTROPIN-RELEASING-HORMONE AGONISTS IN THE TREATMENT OF GIRLS WITH CENTRAL PRECOCIOUS PUBERTY
    BREYER, P
    HAIDER, A
    PESCOVITZ, OH
    [J]. CLINICAL OBSTETRICS AND GYNECOLOGY, 1993, 36 (03): : 764 - 772
  • [4] Combined treatment with gonadotropin-releasing hormone analog and growth hormone in central precocious puberty
    Pasquino, AM
    Municchi, G
    Pucarelli, I
    Segni, M
    Mancini, MA
    Troiani, S
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1996, 81 (03): : 948 - 951
  • [5] Electrocardiogram Changes Following the Treatment with Gonadotropin-Releasing Hormone Agonists in Patients with Precocious Puberty
    Shiva, Siamak
    Samadi, Mahmoud
    Bagherzadeh, Ali
    Sadat-Ebrahimi, Seyyed-Reza
    [J]. INTERNATIONAL JOURNAL OF PEDIATRICS-MASHHAD, 2021, 9 (11): : 14867 - 14876
  • [6] Gonadotropin-releasing hormone analogs treatment in girls with central precocious puberty and early fast puberty
    Lerman, Leiat
    Yackobovitch-Gavan, Michal
    Phillip, Moshe
    Shalitin, Shlomit
    [J]. PEDIATRIC RESEARCH, 2024, 95 (04) : 1051 - 1059
  • [7] Effect of Gonadotropin-Releasing Hormone Agonist Treatment in Boys with Central Precocious Puberty and Early Puberty
    Kim, Eun Young
    Yi, Kyung Hee
    Lee, Jae Hee
    [J]. HORMONE RESEARCH IN PAEDIATRICS, 2018, 90 : 581 - 581
  • [8] Idiopathic scoliosis in girls with central precocious puberty: Incidence and effect of gonadotropin-releasing hormone agonists
    Chung, Lindsey Yoojin
    Nam, Hyo-Kyoung
    Rhie, Young-Jun
    Huh, Rimm
    Lee, Kee-Hyoung
    [J]. HORMONE RESEARCH IN PAEDIATRICS, 2019, 91 : 262 - 262
  • [9] THE INFLUENCE OF GONADOTROPIN-RELEASING HORMONE AGONISTS ON BODY MASS INDEX IN GIRLS WITH CENTRAL PRECOCIOUS PUBERTY
    Lee, Jieun
    Kim, Jae Hyun
    [J]. HORMONE RESEARCH IN PAEDIATRICS, 2017, 88 : 179 - 180
  • [10] Gonadotropin-releasing hormone analogs treatment in girls with central precocious puberty and early fast puberty
    Leiat Lerman
    Michal Yackobovitch-Gavan
    Moshe Phillip
    Shlomit Shalitin
    [J]. Pediatric Research, 2024, 95 : 1051 - 1059
12345