Single-bead analysis in combinatorial chemistry

被引：21
|
作者：
Yan, B [1 ]
机构：
[1] ChemRx Div Discovery Partners Int, San Francisco, CA 94080 USA
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2002年 / 6卷 / 03期
关键词：
D O I：
10.1016/S1367-5931(02)00325-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Notable limitations have previously prevented the wide application of split synthesis. However, recent developments in highly condensed and miniaturized biological screening and single-bead analysis methods have argued for a revival of split combinatorial synthesis. Although there are still many challenges, we are now in a much better position to accomplish high-throughput analysis and screening of one-bead-one-compound libraries.
引用
收藏
页码：328 / 332
页数：5
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