Metabolic and cardiovascular complications of highly active antiretroviral therapy for HIV infection

被引：65
|
作者：
Barbaro, G [1 ]
机构：
[1] Univ Roma La Sapienza, Dept Med Pathophysiol, Rome, Italy
来源：
CURRENT HIV RESEARCH | 2006年 / 4卷 / 01期
关键词：
human immunodeficiency virus; highly active antiretroviral therapy; nucleoside reverse transcriptase inhibitors; protease inhibitors; metabolic syndome; cardiovascular disease;
D O I：
10.2174/157016206775197664
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Highly active antiretroviral therapy (HAART) regimens, especially those including protease inhibitors have been shown to cause, in a high proportion of HIV-infected patients, a metabolic syndrome (lipodystrophy/lipoatrophy, dyslipidemia, type 2 diabetes mellitus, insulin resistance) that may be associated with an increased risk of cardiovascular disease. A careful stratification of the cardiovascular risk of HIV-infected patients under HAART is needed according to the most recent clinical guidelines.
引用
收藏
页码：79 / 85
页数：7
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