Oestrogen receptor β:: what it means for patients with breast cancer

被引：106
|
作者：
Speirs, V
Carder, PJ
Lane, S
Dodwell, D
Lansdown, MR
Hanby, AM
机构：
[1] Univ Leeds, Mol Med Unit, Leeds, W Yorkshire, England
[2] Univ Leeds, Acad Unit Pathol, Leeds, W Yorkshire, England
[3] Leeds Teaching Hosp NHS Trust, Breast Unit, Leeds, W Yorkshire, England
来源：
LANCET ONCOLOGY | 2004年 / 5卷 / 03期
关键词：
D O I：
10.1016/S1470-2045(04)01413-5
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Oestrogen receptor (ER) a is a well established prognostic marker in breast cancer, and all patients who are ERalpha positive receive tamoxifen as adjuvant endocrine therapy. Although ERalpha predicts a favourable disease outcome, the usefulness of ERbeta as a clinical prognostic marker remains to be defined. Here, we outline the history of both ERs and discuss the implications ERbeta has to patients with breast cancer.
引用
收藏
页码：174 / 181
页数：10
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