A Microwave Ring Resonator Based Glucose Sensor

被引:27
|
作者
Camli, Berk [1 ]
Kusakci, Emre [1 ]
Lafci, Berkan [2 ]
Salman, Seyhan [3 ]
Torun, Hamdi [1 ,4 ]
Yalcinkaya, Arda [1 ,4 ]
机构
[1] Bogazici Univ, Dept Elect & Elect Engn, TR-34342 Istanbul, Turkey
[2] Bogazici Univ, Dept Biochem & Engn, TR-34342 Istanbul, Turkey
[3] Bilgi Univ, Dept Genet & Bioengn, TR-34060 Istanbul, Turkey
[4] Bogazici Univ, Ctr Life Sci & Technol, TR-34342 Istanbul, Turkey
关键词
Metamaterials; split ring resonators; biosensors; glucose; GOx; BIOSENSORS;
D O I
10.1016/j.proeng.2016.11.127
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A microwave ring resonator based glucose detecting biosensor incorporating glucose oxidase enzyme is presented. Sensor uses a split ring resonator as a transducer, where the sensing operation is done by the observation of shifts in its resonant frequency. Resonator was fabricated with basic fabrication techniques and the enzyme was immobilized via conductive polymer agent PEDOT: PSS. Experimentally observed redshift of resonant frequency of the sensor in response to different loading conditions are in agreement with simulation results and theoretical expectations. Sensor selectivity is confirmed with control experiments conducted with NaCl solutions. Experiments done with different glucose solution concentrations yielded a sensor sensitivity of 0.174MHz/mgml(-1). (C) 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.
引用
收藏
页码:465 / 468
页数:4
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