Development and Validation of a Sensitive Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Assay for the Simultaneous Quantification of Midostaurin (PKC412) and Its Two Major Metabolites: A Suitable Tool for the Monitoring of the Drug in Patients Suffering From Advanced Systemic Mastocytosis

被引:1
|
作者
Bourget, Philippe [1 ]
Chandesris, Marie-Olivia [2 ]
Amin, Alexandre [1 ]
Vidal, Fabrice [1 ]
Merlette, Christophe [1 ]
Hirsh, Isabelle [3 ]
Carvalhosa, Ana [2 ]
Mogenet, Agnes [4 ]
Broissand, Christine [1 ]
Giraud, Berenice [1 ]
Frenzel, Laurent [2 ]
Damaj, Gandhi [3 ]
Lortholary, Olivier [5 ]
Hermine, Olivier [2 ]
机构
[1] Hop Necker Enfants Malad, Dept Clin Pharm, Paris, France
[2] Hop Necker Enfants Malad, Dept Hematol, Paris, France
[3] Hop Necker Enfants Malad, French Reference Ctr Mastocytosis CEREMAST, Paris, France
[4] Hop Necker Enfants Malad, Clin Invest Dept CIC, Paris, France
[5] Hop Necker Enfants Malad, Infect Dis Dept SMIT, Paris, France
关键词
D O I
10.1182/blood.V120.21.4913.4913
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
4913
引用
收藏
页数:2
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    Walker, Katie A.
    Vignola, Justin N.
    Rudd, Trinity K.
    Cadieux, C. Linn
    diTargiani, Robert C.
    [J]. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2025, 1251
  • [2] Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay to quantify serum voriconazole
    Mak, Justin
    Sujishi, Kirk K.
    French, Deborah
    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2015, 986 : 94 - 99
  • [3] Development and validation of a sensitive, simple, and rapid method for simultaneous quantitation of atorvastatin and its acid and lactone metabolites by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
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    [J]. Analytical and Bioanalytical Chemistry, 2011, 400 : 423 - 433
  • [4] Development and validation of a sensitive, simple, and rapid method for simultaneous quantitation of atorvastatin and its acid and lactone metabolites by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
    Macwan, Joyce S.
    Ionita, Ileana A.
    Dostalek, Miroslav
    Akhlaghi, Fatemeh
    [J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2011, 400 (02) : 423 - 433
  • [5] Development and validation of a sensitive LC-MS/MS assay for the simultaneous quantification of allitinib and its two metabolites in human plasma
    Lin, Lishan
    Gao, Zhiwei
    Chen, Xiaoyan
    Zhong, Dafang
    [J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013, 86 : 49 - 55
  • [6] Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of voriconazole in human cerebrospinal fluid
    Dong, Liuhan
    Bai, Nan
    Wang, Tianlin
    Cai, Yun
    [J]. ANALYTICAL METHODS, 2021, 13 (39) : 4585 - 4593
  • [7] Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of tigecycline in rat brain tissues
    Munyeza, Chiedza F.
    Shobo, Adeola
    Baijnath, Sooraj
    Bratkowska, Dominika
    Naiker, Suhashni
    Bester, Linda A.
    Singh, Sanil D.
    Maguire, Glenn E. M.
    Kruger, Hendrik G.
    Naicker, Tricia
    Govender, Thavendran
    [J]. BIOMEDICAL CHROMATOGRAPHY, 2016, 30 (06) : 837 - 845
  • [8] Liquid chromatography-tandem mass spectrometry assay for therapeutic drug monitoring of the tyrosine kinase inhibitor, midostaurin, in plasma from patients with advanced systemic mastocytosis
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    Amin, Alexandre
    Chandesris, Marie-Olivia
    Vidal, Fabrice
    Merlette, Christophe
    Hirsch, Isabelle
    Cabaret, Laure
    Carvalhosa, Ana
    Mogenet, Agnes
    Frenzel, Laurent
    Damaj, Gandhi
    Lortholary, Olivier
    Hermine, Olivier
    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, 944 : 175 - 181
  • [9] Simultaneous quantification of 18 different phytocannabinoids in serum using a highly sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method
    Scheunemann, A.
    Elsner, K.
    Germerott, T.
    Hess, C.
    Roehrich, J.
    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 1173
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    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 1179