Design, synthesis and biological evaluation of potential inhibitors of the HIF-1 \#945;:HIF-1\#946; protein-protein interaction

被引:0
|
作者
Bendiabdellah, Yassine
Zinzalla, Giovanna
Badarch, Uranchimeg
Nahar, Kazi
Antonow, Dyeison
Rahman, Khondaker
Shoemaker, Robert
Melillo, Giovanni
Thurston, David
机构
[1] Univ London, CR UK Prot Prot Interact Drug Discovery Res Grp, London, England
[2] NCI, SAIC Frederick Inc, Frederick, MD 21701 USA
[3] NCI, Dev Therapeut Program, Frederick, MD 21701 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4646
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Next Generation SICLOPPS Screening for the Identification of Inhibitors of the HIF-1α/HIF-1β Protein-Protein Interaction
    McDermott, Alexander
    Windeln, Leonie M.
    Valentine, Jacob S. D.
    Baldassarre, Leonardo
    Foster, Andrew D.
    Tavassoli, Ali
    [J]. ACS CHEMICAL BIOLOGY, 2024,
  • [2] Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interaction
    Cardoso, Rosa
    Love, Robert
    Nilsson, Carol L.
    Bergqvist, Simon
    Nowlin, Dawn
    Yan, Jiangli
    Liu, Kevin K. -C.
    Zhu, Jing
    Chen, Ping
    Deng, Ya-Li
    Dyson, H. Jane
    Greig, Michael J.
    Brooun, Alexei
    [J]. PROTEIN SCIENCE, 2012, 21 (12) : 1885 - 1896
  • [3] Anticancer osmium complex inhibitors of the HIF-1α and p300 protein-protein interaction
    Chao Yang
    Wanhe Wang
    Guo-Dong Li
    Hai-Jing Zhong
    Zhen-Zhen Dong
    Chun-Yuen Wong
    Daniel W. J. Kwong
    Dik-Lung Ma
    Chung-Hang Leung
    [J]. Scientific Reports, 7
  • [4] Anticancer osmium complex inhibitors of the HIF-1α and p300 protein-protein interaction
    Yang, Chao
    Wang, Wanhe
    Li, Guo-Dong
    Zhong, Hai-Jing
    Dong, Zhen-Zhen
    Wong, Chun-Yuen
    Kwong, Daniel W. J.
    Ma, Dik-Lung
    Leung, Chung-Hang
    [J]. SCIENTIFIC REPORTS, 2017, 7
  • [5] Small-Molecule Proteomimetic Inhibitors of the HIF-1α-p300 Protein-Protein Interaction
    Burslem, George M.
    Kyle, Hannah F.
    Breeze, Alexander L.
    Edwards, Thomas A.
    Nelson, Adam
    Warriner, Stuart L.
    Wilson, Andrew J.
    [J]. CHEMBIOCHEM, 2014, 15 (08) : 1083 - 1087
  • [6] Synthesis of Uscharin Oxime Analogues and Their Biological Evaluation as HIF-1 Inhibitors
    Zhou, Xiaobo
    Xiao, Riping
    Chen, Ming
    Bai, Li-Ping
    [J]. CHEMISTRYSELECT, 2020, 5 (42): : 12869 - 12872
  • [7] Synthesis and Evaluation of Celastrol Derivatives as HIF-1α Inhibitors
    Xiaoqun Ren
    Linlin Cui
    Yang Wang
    Huayun Li
    Guanghuan Shen
    [J]. Chemistry of Natural Compounds, 2022, 58 : 1075 - 1078
  • [8] SYNTHESIS AND EVALUATION OF CELASTROL DERIVATIVES AS HIF-1α INHIBITORS
    Ren, Xiaoqun
    Cui, Linlin
    Wang, Yang
    Li, Huayun
    Shen, Guanghuan
    [J]. CHEMISTRY OF NATURAL COMPOUNDS, 2022, 58 (06) : 1075 - 1078
  • [9] Design, synthesis, and biological evaluation of manassantin analogues for HIF-1α inhibition
    Kwon, Do-Yeon
    Park, Kyunghye
    Weitzel, Douglas
    Lee, Sun Hee
    Stephenson, Tesia
    Lee, Chen-Ting
    Chi, Jen-Tsan
    Mook, Robert
    Dewhirst, Mark
    Lee, You Mie
    Hong, Jiyong
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [10] Modulation of HIF-1\#945; mRNA processing by Aminoflavone: a novel mechanism of HIF-1\#945; inhibition in breast cancer cells
    Terzuoli, Erika
    Uranchimeg, Badarch
    Rapisarda, Annamaria
    Burger, Angelika
    Ziche, Marina
    Melillo, Giovanni
    [J]. CANCER RESEARCH, 2009, 69