Cell growth is a fundamental process for every cell but its pleiotropic complexity makes it difficult to comprehend. Global aspects of cellular growth, like the overall determinants of growth rate are not well understood. Here we examine the cell growth pattern of the fission yeast Schizosaccharomyces pombe during the mitotic and meiotic cell cycles. We also explore recent findings illuminating aspects of cell size homeostasis and cell growth regulation, and propose that there are global controls over growth acting at the level of the cell.
机构:
Mem Sloan Kettering Canc Ctr, Sloan Kettering Inst, Program Mol Biol, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Sloan Kettering Inst, Program Mol Biol, New York, NY 10065 USA
Callegari, A. John
Kelly, Thomas J.
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机构:
Mem Sloan Kettering Canc Ctr, Sloan Kettering Inst, Program Mol Biol, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Sloan Kettering Inst, Program Mol Biol, New York, NY 10065 USA