Global control of cell growth in fission yeast and its coordination with the cell cycle

被引:29
|
作者
Navarro, Francisco J. [1 ]
Weston, Louise [1 ]
Nurse, Paul [1 ,2 ,3 ]
机构
[1] Canc Res UK, London Res Inst, Cell Cycle Lab, London WC2A 3LY, England
[2] Rockefeller Univ, Lab Yeast Genet & Cell Biol, New York, NY 10065 USA
[3] Francis Crick Inst, London NW1 2BE, England
基金
英国惠康基金;
关键词
SCHIZOSACCHAROMYCES-POMBE; PROTEIN-KINASE; SIZE CONTROL; RNA; DIVISION; MEIOSIS; MUTANTS; PATHWAY; PATTERN; LENGTH;
D O I
10.1016/j.ceb.2012.10.015
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Cell growth is a fundamental process for every cell but its pleiotropic complexity makes it difficult to comprehend. Global aspects of cellular growth, like the overall determinants of growth rate are not well understood. Here we examine the cell growth pattern of the fission yeast Schizosaccharomyces pombe during the mitotic and meiotic cell cycles. We also explore recent findings illuminating aspects of cell size homeostasis and cell growth regulation, and propose that there are global controls over growth acting at the level of the cell.
引用
收藏
页码:833 / 837
页数:5
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