First-in-Human experience with LJN452, an orally available non-bile acid FXR agonist, demonstrates potent activation of FXR in healthy subjects

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作者
Badman, Michael K. [1 ]
Desai, Sachin [1 ]
Laffitte, Bryan [2 ]
Decristofaro, Marc [1 ]
Lin, TsuHan [1 ]
Chen, Jin [1 ]
Reilly, John F. [1 ]
Klickstein, Lloyd [1 ]
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[1] Novartis Inst BioMed Res, Cambridge, MA USA
[2] Novartis Res Fdn, Genom Inst, San Diego, CA USA
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R57 [消化系及腹部疾病];
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32
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页码:16A / 17A
页数:2
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