Overactive Tgfβ Signaling in Smooth Muscle Cells Induces Hypertension in Mice Through Increased Myogenic Tone and is Responsible for Increased Myogenic Tone in Resistance Vessels of Hypertensive Patients

被引:0
|
作者
Carnevale, Daniela
Casaburo, Manuel
Bizzotto, Dario
Cugino, Daniela
Selvetella, Giulio
Innocenzi, Gualtiero
Bressan, Giorgio
Lembo, Giuseppe
机构
关键词
hypertension; vascular resistance; Growth factors;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
18266
引用
收藏
页数:2
相关论文
共 15 条
  • [1] Increased Coronary Myogenic Tone in Patients With Poorly Controlled Hypertension
    Feng, Jun
    Liu, Yuhong
    Phillips, Ronald
    Del Re, Andrew
    Ehsan, Afshin
    Kononov, Martin
    Sodha, Neel
    Sellke, Frank W.
    [J]. CIRCULATION, 2021, 144
  • [2] THE RELATIONSHIP BETWEEN INCREASED MYOGENIC TONE AND HYPORESPONSIVENESS IN VASCULAR SMOOTH-MUSCLE OF SPONTANEOUSLY HYPERTENSIVE RATS
    FITZPATRICK, DF
    SZENTIVANYI, A
    [J]. CLINICAL AND EXPERIMENTAL HYPERTENSION, 1980, 2 (06) : 1023 - 1037
  • [3] Smooth muscle glutathione depletion contributes to increased myogenic tone in resistance arteries of type-2 diabetic mice
    Velmurugan, Gopal V.
    White, Carl
    [J]. FASEB JOURNAL, 2012, 26
  • [4] Subarachnoid hemorrhage enhances peripheral resistance artery myogenic tone through smooth muscle TNFa
    Levy, Andrew S.
    Kroestch, Jeffery T.
    D'Abbondanza, Josephine
    Yagi, Kenji
    Nedospasov, Sergei
    Offermanns, Stefan
    Lidington, Darcy
    MacDonald, R. Loch
    Bolz, Steffen-Sebastian
    [J]. ANGIOGENESIS, 2014, 17 (01) : 317 - 317
  • [5] Opioids Induce Proliferation in Vascular Smooth Muscle Cells Leading to an Increase in Myogenic Tone in Resistance Arteries
    Tomcho, Jeremy C.
    Edwards, Jonnelle
    Bearss, Nicole R.
    McCarthy, Cameron G.
    Joe, Bina
    Wenceslau, Camilla F.
    [J]. HYPERTENSION, 2019, 74
  • [6] Poorly controlled hypertension is associated with increased coronary myogenic tone in patients undergoing cardiac surgery with cardiopulmonary bypass
    Sabe, Sharif A.
    Kononov, Martin A.
    Bellam, Krishna G.
    Sodha, Neel
    Ehsan, Afshin
    Jackson, William F.
    Feng, Jun
    Sellke, Frank W.
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2023, 165 (06): : E256 - E267
  • [7] Increased arterial smooth muscle Ca2+ signaling, vasoconstriction, and myogenic reactivity in Milan hypertensive rats
    Linde, Cristina I.
    Karashima, Eiji
    Raina, Hema
    Zulian, Alessandra
    Wier, Withrow G.
    Hamlyn, John M.
    Ferrari, Patrizia
    Blaustein, Mordecai P.
    Golovina, Vera A.
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2012, 302 (03): : H611 - H620
  • [8] Increased ischemic duration decreases F-actin content in cerebral artery vascular smooth muscle and diminshes myogenic tone
    Cipolla, MJ
    Hammer, ES
    Curry, AB
    [J]. FASEB JOURNAL, 2000, 14 (04): : A426 - A426
  • [9] Hypertension Down Regulates Emilin1 in the Extracellular Matrix of Resistance Arteries in Humans and Mice, in Order to Increase the Myogenic Tone Through Overactive TGFβ, Thus Contributing to Blood Pressure Regulation
    Carnevale, Daniela
    Perrotta, Marialuisa
    Fardella, Stefania
    Casaburo, Manuel
    Bizzotto, Dario
    Selvetella, Giulio
    Innocenzi, Gualtiero
    Bressan, Giorgio
    Lembo, Giuseppe
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2016, 36
  • [10] Increased myogenic tone in skeletal muscle arterioles of diabetic rats.: Possible role of increased activity of smooth muscle Ca2+ channels and protein kinase C
    Ungvari, Z
    Pacher, P
    Kecskemeti, V
    Papp, G
    Szollár, L
    Koller, A
    [J]. CARDIOVASCULAR RESEARCH, 1999, 43 (04) : 1018 - 1028