Synthesis and Biological Activity of Substituted Spiro[chromene-4,3-indoles] and Spiro[indole-3,4-quinolines]

被引：10
|
作者：
Pogosyan, S. A. [1 ]
Pogosyan, M. V. [1 ]
Aleksanyan, L. R. [1 ]
Safaryan, A. S. [1 ]
Arakelyan, A. G. [1 ]
机构：
[1] Natl Acad Sci Armenia, Mndzhoyan Inst Fine Organ Chem, Sci Technol Ctr Organ & Pharmaceut Chem, Pr Azatutyan 26, Yerevan 0014, Armenia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 54卷 / 12期
关键词：
D O I：
10.1134/S1070428018120254
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New substituted spiro[chromene-4,3-indoles] and spiro[indole-3,4-quinolines] have been synthesized in 35-65% yields by one-pot regioselective three-component condensation of N-substituted isatins with two active methylene compounds.
引用
收藏
页码：1860 / 1863
页数：4
相关论文
共 50 条
  • [1] Synthesis and Biological Activity of Substituted Spiro[chromene-4,3′-indoles] and Spiro[indole-3,4′-quinolines]
    S. A. Pogosyan
    M. V. Pogosyan
    L. R. Aleksanyan
    A. S. Safaryan
    A. G. Arakelyan
    Russian Journal of Organic Chemistry, 2018, 54 : 1860 - 1863
  • [2] Synthesis of new heterocyclic systems—substituted spiro[chromene-4,3′-indoles] and spiro[indole-3,4′-quinolines]
    S. A. Pogosyan
    Dzh. A. Avakimyan
    H. M. Stepanyan
    Russian Journal of Organic Chemistry, 2016, 52 : 1308 - 1311
  • [3] Synthesis of new heterocyclic systems-substituted spiro[chromene-4,3′-indoles] and spiro[indole-3,4′-quinolines]
    Pogosyan, S. A.
    Avakimyan, Dzh. A.
    Stepanyan, H. M.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 52 (09) : 1308 - 1311
  • [4] Synthesis of Spiro[benzo[h]chromene-4,3′-indoles] and Spiro[benzo[f]chromene-1,3′-indoles]
    S. H. Poghosyan
    M. V. Poghosyan
    Russian Journal of Organic Chemistry, 2019, 55 : 1821 - 1825
  • [5] Synthesis of Spiro[benzo[h]chromene-4,3′-indoles] and Spiro[benzo[f]chromene-1,3'-indoles]
    Poghosyan, S. H.
    Poghosyan, M. V.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 55 (12) : 1821 - 1825
  • [6] Synthesis of Novel Spiro[chromene-4,3'-indolines] and Spiro(indoline-3,4'-pyrano[3,2-h]quinolines)
    Pogosyan, S. A.
    Pogosyan, M., V
    Harutyunyan, A. A.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2020, 56 (02) : 213 - 217
  • [7] Synthesis of Novel Spiro[chromene-4,3'-indolines] and Spiro(indoline-3,4'-pyrano[3,2-h]quinolines)
    S. A. Pogosyan
    M. V. Pogosyan
    A. A. Harutyunyan
    Russian Journal of Organic Chemistry, 2020, 56 : 213 - 217
  • [8] FACILE SYNTHESIS OF SOME NOVEL SPIRO[INDOLE-3,4'-DIPYRROLOPYRAN] DERIVATIVES
    DANDIA, A
    SEHGAL, V
    SINGH, P
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1994, 42 (09) : 1909 - 1911
  • [9] Synthesis of Spiro[indole-3,5′-isoxazoles] with Anticancer Activity via a Formal [4+1]-Spirocyclization of Nitroalkenes to Indoles
    Aksenov, Alexander V.
    Aksenov, Dmitrii A.
    Arutiunov, Nikolai A.
    Aksenov, Nicolai A.
    Aleksandrova, Elena V.
    Zhao, Zhenze
    Du, Liqin
    Kornienko, Alexander
    Rubin, Michael
    JOURNAL OF ORGANIC CHEMISTRY, 2019, 84 (11): : 7123 - 7137
  • [10] Microwave Assisted ZrSiO2 Mediated One-Pot Synthesis of Spiro[chromene-4,3 '-indoline] Derivatives
    Borad, Mayuri A.
    Bhoi, Manoj N.
    Patel, Bhakti N.
    Patel, Hitesh D.
    CURRENT MICROWAVE CHEMISTRY, 2016, 3 (03) : 187 - 193
12345