Network analysis using transitive closure: New methods for exploring networks

被引:1
|
作者
Dougherty, DP [1 ]
Stahlberg, EA
Sadee, W
机构
[1] Ohio State Univ, Math Biosci Inst, Columbus, OH 43210 USA
[2] Ohio Supercomp Ctr, Columbus, OH USA
[3] Ohio State Univ, Dept Pharmacol, Columbus, OH USA
基金
美国国家科学基金会;
关键词
transitive closure; gene network; Floyd-Warshall; path analysis; scale-free; transitivity;
D O I
10.1080/10629360500107857
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
We describe two methods for analysing a complex network which focus on examining changes in the transitive closure of the network under directed and stochastic attack of its edges. Dynamic transitive closure analysis (DTCA) examines changes in critical transitive path for increasingly stringent edge length tolerance. Context specific DTCA is a fuzzy extension of DTCA, which examines changes in DTCA under randomly perturbed transitive contexts. We find that such strategies allow a researcher to identify highly connected elements within a network and uncover related sub-networks. Application to simulated random graphs demonstrates that these methods can be used to determine local network connections as well as quantify the overall transitive natures of the network. We have developed an adjustable resolution O(N 3 ) parallel algorithm to carry out these analyses which scales nearly linearly with the number of nodes in the network.
引用
收藏
页码:539 / 551
页数:13
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