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Chinese Acad Med Sci & Peking Union Med Coll, Natl Ctr Cardiovasc Dis, State Key Lab Cardiovasc Med, Dept Cardiopulm Bypass,Fuwai Hosp, Beijing, Peoples R China Chinese Acad Med Sci & Peking Union Med Coll, Natl Ctr Cardiovasc Dis, State Key Lab Cardiovasc Med, Dept Cardiopulm Bypass,Fuwai Hosp, Beijing, Peoples R China