TNF-alpha inhibitors in Systemic Lupus Erythematosus. A case report and a systematic literature review

被引：10

作者：

Mosca, Marta ^{[1
]}

Tani, Chiara ^{[1
]}

Filice, Maria Elena ^{[3
]}

Carli, Linda ^{[1
]}

Delle Sedie, Andrea ^{[2
]}

Vagnani, Sabrina ^{[1
]}

Della Rossa, Alessandra ^{[2
]}

Baldini, Chiara ^{[1
]}

Bombardieri, Stefano ^{[1
]}

机构：

[1] Univ Pisa, Dept Clin & Expt Med, Rheumatol Unit, I-56126 Pisa, Italy

[2] Azienda Osped Univ Pisana, Rheumatol Unit, Pisa, Italy

[3] Azienda Osped Univ Pisana, Pathol Unit, Pisa, Italy

来源：

MODERN RHEUMATOLOGY | 2015年 / 25卷 / 04期

关键词：

Anti-TNF therapy; Joint involvement; Systemic lupus erythematosus treatment targets; NECROSIS-FACTOR-ALPHA; TISSUE DISEASES UCTD; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; AUTOIMMUNE-DISEASES; OPEN-LABEL; INFLIXIMAB; EFFICACY; ETANERCEPT; SAFETY; THERAPY;

D O I：

10.3109/14397595.2013.844306

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Joint involvement is a common manifestation of systemic lupus erythematosus (SLE) and is described as a non-erosive mild synovitis. However some SLE patients may present a more severe joint involvement requiring aggressive therapy. We describe the case of a SLE patient with a severe arthritis unresponsive to methotrexate, successfully treated with anti-TNF-alpha drug as induction therapy and we report the results of a systematic literature review on the use of TNF-alpha inhibitors in SLE.

引用

页码：642 / 645

页数：4

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