NMR assignment of the N-terminal region of human La free and in complex with RNA

被引:10
|
作者
Sanfelice, Domenico [1 ]
Kelly, Geoff [2 ]
Curry, Stephen [3 ]
Conte, Maria R. [1 ]
机构
[1] Kings Coll London, Randall Div Cell & Mol Biophys, London SE1 1UL, England
[2] Natl Inst Med Res, Biomed NMR Ctr, London NW7 1AA, England
[3] Univ London Imperial Coll Sci Technol & Med, Blackett Lab, Biophys Sect, London SW7 2AZ, England
基金
英国医学研究理事会; 英国惠康基金;
关键词
La autoantigen; NMR resonance assignment; RNA interaction;
D O I
10.1007/s12104-008-9097-5
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
H-1, N-15 and C-13 chemical shift assignments are presented for the N-terminal region of human La protein, in the apo and 5'-UUUU RNA-bound state. Secondary structure analysis shows conformational changes in the interdomain linker upon complex formation.
引用
收藏
页码:107 / 109
页数:3
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