Chemokines: the (un)usual suspects in pancreatic cancer neural invasion

被引：6
|
作者：
Demir, Ihsan Ekin [1 ,2 ,3 ]
Mota Reyes, Carmen [1 ,2 ,3 ]
机构：
[1] Tech Univ Munich, Sch Med, Dept Surg, Klinikum Rechts Isar, Munich, Germany
[2] Acibadem Mehmet Ali Aydinlar Univ, Sch Med, Dept Gen Surg, HPB Unit, Istanbul, Turkey
[3] Tech Univ Munich, Sch Med, Klinikum Rechts Isar, CRC 1321 Modelling & Targeting Pancreat Canc, Munich, Germany
来源：
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY | 2021年 / 18卷 / 04期
关键词：
PAIN;
D O I：
10.1038/s41575-020-0329-1
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Pancreatic cancer is notorious for its affinity for invading nerves. A new study using a systematic unbiased RNA-interference screen of neuronal chemokines in cocultures of mouse sensory neurons and pancreatic cancer cells has now identified CCL21 and CXCL10 as key mediators of neural invasion, neural remodelling and pain in pancreatic cancer.
引用
收藏
页码：221 / 222
页数：2
相关论文
共 50 条
  • [1] Chemokines: the (un)usual suspects in pancreatic cancer neural invasion
    Ihsan Ekin Demir
    Carmen Mota Reyes
    [J]. Nature Reviews Gastroenterology & Hepatology, 2021, 18 : 221 - 222
  • [2] Commentary: The (un) usual suspects
    Chen, Jonathan M.
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2020, 160 (01): : 200 - 201
  • [3] Revolutionizing Cancer Treatment: Unveiling New Frontiers by Targeting the (Un)Usual Suspects
    Costa, Valerio
    Giovannetti, Elisa
    Lonardo, Enza
    [J]. CANCERS, 2024, 16 (01)
  • [4] HYPERCALCEMIA AND CANCER; NOT THE USUAL SUSPECTS
    Giro, Pedro
    Knoeckel, Julie
    [J]. JOURNAL OF GENERAL INTERNAL MEDICINE, 2020, 35 (SUPPL 1) : S482 - S483
  • [5] 1997 research: Round up the (un)usual suspects
    不详
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1997, 36 (10): : 1328 - 1328
  • [6] Role of chemokines in pain and perineural invasion in pancreatic cancer
    Gandla, J.
    Hirth, M.
    Michalski, C.
    Weis, C. A.
    Kuner, R.
    [J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2017, 390 : S5 - S5
  • [7] The (Un)usual Suspects? A Measurement Community in Search of Its Identity
    Rupp, Andre A.
    Templin, Jonathan
    [J]. MEASUREMENT-INTERDISCIPLINARY RESEARCH AND PERSPECTIVES, 2009, 7 (02) : 115 - 121
  • [8] Cancer genomics: Beyond the usual suspects
    Pentimalli, Francesca
    [J]. NATURE REVIEWS GENETICS, 2007, 8 (04) : 250 - 251
  • [9] The nature of neural invasion by pancreatic cancer
    Kayahara, Masato
    Nakagawara, Hisatoshi
    Kitagawa, Hirohisa
    Ohta, Tetsuo
    [J]. PANCREAS, 2007, 35 (03) : 218 - 223
  • [10] Neural invasion in the staging of pancreatic cancer
    Pour, PM
    Bell, RH
    Batra, SK
    [J]. PANCREAS, 2003, 26 (04) : 322 - 325
12345