A facile one-pot, three-component synthesis of 3,3′-(4-arylpyridine-2,6-diyl)bis(2H-chromen-2-one) derivatives under microwave irradiation

被引：6
|
作者：
Zhou, Jian-Feng [1 ]
Sun, Xiao-Jun [1 ]
Lou, Feng-Wen [1 ]
Lv, Meng [2 ]
Zhang, Lu-Lu [2 ]
机构：
[1] Huaiyin Normal Univ, Sch Chem & Chem Engn, Jiangsu Key Lab Chem Low Dimens Mat, Huaian 223300, Peoples R China
[2] Ningxia Univ, Sch Chem & Chem Engn, Yinchuan 750021, Peoples R China
来源：
RESEARCH ON CHEMICAL INTERMEDIATES | 2013年 / 39卷 / 03期
关键词：
3,3 '-(4-Arylpyridine-2,6-diyl)bis(2H-chromen-2-one); 3-Acetylcoumarin; Multicomponent reaction; Microwave irradiation; TOPOISOMERASE-I INHIBITION; SUBSTITUTED PYRIDINES; TRYPANOSOMA-CRUZI; CYTOTOXICITY; COMPLEXES;
D O I：
10.1007/s11164-012-0696-5
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A series of 3,3'-(4-arylpyridine-2,6-diyl)bis(2H-chromen-2-one) derivatives have been synthesized by the one-pot, three-component reaction of 3-acetylcoumarin, an aromatic aldehyde, and ammonium acetate in acetic acid under microwave irradiation. This procedure has the major advantages of short reaction time, good yields, low energy consumption, easy operation, and environmental friendliness. All of the products were characterized by IR and NMR spectroscopy, MS, and elemental analysis.
引用
收藏
页码：1401 / 1408
页数：8
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