Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient

被引：10
|
作者：
Chou, Kuan-Nien [1 ]
Lin, Yu-Chieh [2 ]
Liu, Ming-Ying [1 ]
Chang, Ping-Ying [3 ]
机构：
[1] Tri Serv Gen Hosp, Natl Def Med Ctr, Dept Neurol Surg, Taipei, Taiwan
[2] Tri Serv Gen Hosp, Natl Def Med Ctr, Dept Pathol, Taipei, Taiwan
[3] Tri Serv Gen Hosp, Natl Def Med Ctr, Dept Internal Med, Div Hematol & Oncol, Taipei, Taiwan
来源：
JOURNAL OF CLINICAL NEUROSCIENCE | 2014年 / 21卷 / 04期
关键词：
Glioblastoma multiforme; Secondary acute lymphoblastic leukemia; Temozolomide; Therapy-related acute lymphoblastic leukemia; 2ND MALIGNANCY; GIMEMA ARCHIVE; MYELODYSPLASIA;
D O I：
10.1016/j.jocn.2013.07.032
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Temozolomide (TMZ), an alkylating agent, is widely used for treating high-grade gliomas. TMZ has been reported to cause secondary myelodysplastic syndrome and acute myeloid leukemia. However, TMZ-related acute lymphoblastic leukemia is rare. Here we describe a 54-year-old woman with glioblastoma multiforme, who developed precursor-B acute lymphoblastic leukemia with translocation (4;11)(q21;q23) after 15 months of TMZ treatment. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：701 / 704
页数：4
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