Thermal Analysis in the Pharmaceutical Research and Drug Development

被引：0
|
作者：
Seilerova, Lenka [1 ]
Brusova, Hana [2 ]
Kratochvil, Bohumil [1 ]
Krejcik, Lukas [2 ]
机构：
[1] Vysoka Skola Chemickotechnologicka Praze, Ustav Chem Pevnych Latek, Prague 16628 6, Czech Republic
[2] Zentiva Ks, Prague 10237 10, Czech Republic
来源：
CHEMICKE LISTY | 2012年 / 106卷 / 10期
关键词：
DIFFERENTIAL SCANNING CALORIMETRY; EXCIPIENT COMPATIBILITY; MICROCALORIMETRY; PARACETAMOL; DEGRADATION; STATE; DSC;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Thermal analysis is a valuable method in pharmaceutical research. A wide range of thermal methods are used in drug development like thermogravimetry (TG), differential thermal analysis (DTA), differential scanning calorimetry (DSC) and other sensitive and specific methods. The present review deals with application of these methods in characterization of drugs and excipients, such as their polymorph stability, glass transition temperature, purity analysis and compatibility of drugs.
引用
收藏
页码：890 / 895
页数：6
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