Current and future therapeutical approaches for COVID-19

被引:15
|
作者
Duan, Yongtao [1 ]
Yao, Yongfang [2 ]
Kumar, Senthil Arun [3 ]
Zhu, Hai-Liang [1 ,4 ]
Chang, Junbiao [2 ]
机构
[1] Zhengzhou Univ, Henan Prov Key Lab Childrens Genet & Metab Dis, Childrens Hosp, Zhengzhou 450001, Peoples R China
[2] Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou 450001, Henan, Peoples R China
[3] Zhengzhou Univ, Dept Endocrinol & Metab, Genet, Childrens Hosp, Zhengzhou 450001, Peoples R China
[4] Nanjing Univ, State Key Lab Pharmaceut Biotechnol, Nanjing 210093, Peoples R China
基金
中国国家自然科学基金;
关键词
DRUG DISCOVERY; SARS; PNEUMONIA; PLASMA; ARBIDOL;
D O I
10.1016/j.drudis.2020.06.018
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Coronavirus 2019 (COVID-19), the WHO-classified novel coronavirus of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly become a global pandemic. To tackle both its spread and virulence, research is ongoing worldwide to develop an effective anti-COVID-19 drug or vaccine. In this review, we explore the clinical understanding and severity of COVID-19 emergence across the world, with a focus on China. We also discuss potential therapeutic targets, either host virus based, that could be used to tackle the COVID-19 outbreak.
引用
收藏
页码:1545 / 1552
页数:8
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