Gene Expression Analysis Reveals a Subset of TP53mutant-like AML with Wild Type TP53 and Poor Prognosis

被引：0
|
作者：
Lee, Yoonkyu [1 ,2 ,3 ]
Myers, Chad [2 ,4 ,5 ]
Sachs, Zohar [1 ,2 ,5 ]
机构：
[1] Univ Minnesota, Dept Med, Div Hematol Oncol & Transplantat, Minneapolis, MN USA
[2] Univ Minnesota, Bioinformat & Computat Biol Program, Rochester, MN USA
[3] Univ Minnesota, Minneapolis, MN USA
[4] Univ Minnesota, Dept Comp Sci & Engn, Minneapolis, MN USA
[5] Univ Minnesota, Masonic Canc Ctr, Minneapolis, MN USA
来源：
BLOOD | 2022年 / 140卷
关键词：
D O I：
10.1182/blood-2022-167021
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：9108 / 9109
页数：2
相关论文
共 50 条
  • [1] Machine learning analysis of gene expression reveals TP53 Mutant-like AML with wild type TP53 and poor prognosis
    Lee, Yoonkyu
    Baughn, Linda B.
    Myers, Chad L.
    Sachs, Zohar
    BLOOD CANCER JOURNAL, 2024, 14 (01):
  • [2] The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis
    Leroy, Bernard
    Fournier, Jean Louis
    Ishioka, Chikashi
    Monti, Paola
    Inga, Alberto
    Fronza, Gilberto
    Soussi, Thierry
    NUCLEIC ACIDS RESEARCH, 2013, 41 (D1) : D962 - D969
  • [3] Pathogenic TP53 mutations Are Associated with a Poor Prognosis in De Novo AML
    Lamble, Adam J.
    Ries, Rhonda E.
    Dang, Alice
    Alonzo, Todd A.
    Chisholm, Karen
    Kolekar, Pandurang
    Liu, Yanling
    Tran, Quang
    Cooper, Todd M.
    Aplenc, Richard
    Gamis, Alan S.
    Kolb, Edward A.
    Ma, Xiaotu
    Meshinchi, Soheil
    BLOOD, 2022, 140 : 6297 - 6298
  • [4] Maspin subcellular expression in wild-type and mutant TP53 gastric cancers
    Gurzu, Simona
    Jung, Ioan
    Sugimura, Haruhiko
    Stefan-van Staden, Raluca Ioana
    Yamada, Hidetaka
    Natsume, Hiroko
    Iwashita, Yuji
    Szodorai, Rita
    Szederjesi, Janos
    WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2020, 12 (07) : 741 - 755
  • [5] Maspin subcellular expression in wild-type and mutant TP53 gastric cancers
    Simona Gurzu
    Ioan Jung
    Haruhiko Sugimura
    Raluca Ioana Stefan-van Staden
    Hidetaka Yamada
    Hiroko Natsume
    Yuji Iwashita
    Rita Szodorai
    Janos Szederjesi
    World Journal of Gastrointestinal Oncology, 2020, (07) : 741 - 755
  • [6] Poor survival with wild-type TP53 ovarian cancer?
    Wong, Kwong-Kwok
    Izaguirre, Daisy I.
    Kwan, Suet-Yan
    King, Erin R.
    Deavers, Michael T.
    Sood, Anil K.
    Mok, Samuel C.
    Gershenson, David M.
    GYNECOLOGIC ONCOLOGY, 2013, 130 (03) : 565 - 569
  • [7] Single-Cell Genomics and Proteomics Reveals Venetoclax-Resistant Monocytic Differentiation of TP53 LOH Clones in TP53 Mutant AML
    Ayoub, Edward
    Muftuoglu, Muharrem
    Nishida, Yuki
    Mohanty, Vakul
    Leighton, Jake S.
    Patsilevas, Tallie
    Basyal, Mahesh
    Bedoy, Andrea
    Haferlach, Torsten
    Takahashi, Koichi
    Chen, Ken
    Navin, Nicholas
    Issa, Ghayas C.
    Andreeff, Michael
    BLOOD, 2023, 142
  • [8] Differential angiogenic gene expression in TP53 wild-type and mutant ovarian cancer cell lines
    Davidson, Brittany Anne
    Rubatt, Jennifer M.
    Corcoran, David L.
    Teoh, Deanna K.
    Bernardini, Marcus Q.
    Grace, Lisa A.
    Soper, William John
    Berchuck, Andrew
    Siamakpour-Reihani, Sharareh
    Chen, Wei
    Owzar, Kouros
    Murphy, Susan K.
    Secord, Angeles Alvarez
    FRONTIERS IN ONCOLOGY, 2014, 4
  • [9] Expression signature based on TP53 target genes doesn't predict response to TP53-MDM2 inhibitor in wild type TP53 tumors
    Sonkin, Dmitriy
    ELIFE, 2015, 4
  • [10] Expression of wild-type and mutated TP53 in breast carcinomas
    Baumbusch, LO
    Myhre, S
    Langerod, A
    Bergamaschi, A
    Johnsen, H
    Geisler, S
    Lonning, PE
    Borresen-Dale, AL
    BREAST CANCER RESEARCH, 2005, 7 (Suppl 2) : S53 - S53
12345