Phase I/II study of T-DM1 alone versus T-DM1 and metronomic temozolomide in secondary prevention of HER2-Positive breast cancer brain metastases following stereotactic radiosurgery

被引：0
|
作者：
Zimmer, Alexandra S.
Gril, Brunilde
Steinberg, Seth
Smart, DeeDee
Gilbert, Mark
Armstrong, Teri
Xiao, Lin
Houston, Nicole
Biassou, Nadia
Brastianos, Priscilla
Carter, Scott
Lyden, David C.
Lipkowitz, Stanley
Steeg, Patricia
机构：
[1] NCI, Womens Malignancies Branch, NIH, Bethesda, MD 20892 USA
[2] NCI, NIH, Bethesda, MD 20892 USA
[3] NCI, Radiat Oncol Branch, NIH, Bldg 10, Bethesda, MD 20892 USA
[4] NCI, Neurooncol Branch, NIH, Bethesda, MD 20892 USA
[5] NIH, Neuroradiol, Ctr Clin, Bldg 10, Bethesda, MD 20892 USA
[6] Massachusetts Gen Hosp, Harvard Canc Ctr, Boston, MA 02114 USA
[7] Dana Farber Canc Inst, Boston, MA 02115 USA
[8] Weill Cornell Med, New York, NY USA
来源：
CANCER RESEARCH | 2018年 / 78卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
OT2-06-01
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Phase I/II study of T-DM1 alone versus T-DM1 and metronomic temozolomide in secondary prevention of HER2-positive breast cancer brain metastases following stereotactic radiosurgery.
    Zimmer, Alexandra Dos Santos
    Steinberg, Seth M.
    Smart, DeeDee Kay
    Gilbert, Mark R.
    Armstrong, Terri
    Burton, Eric
    Houston, Nicole D.
    Biassou, Nadia
    Gril, Brunilde
    Brastianos, Priscilla Kaliopi
    Carter, Scott L.
    Lyden, David
    Lipkowitz, Stanley
    Steeg, Patricia Schriver
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [2] Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases
    Jenkins, Sarah
    Zhang, Wei
    Steinberg, Seth M.
    Nousome, Darryl
    Houston, Nicole
    Wu, Xiaolin
    Armstrong, Terri S.
    Burton, Eric
    Smart, Dee Dee
    Shah, Ritu
    Peer, Cody J.
    Mozarsky, Brett
    Arisa, Oluwatobi
    Figg, William D.
    Mendoza, Tito R.
    Vera, Elizabeth
    Brastianos, Priscilla
    Carter, Scott
    Gilbert, Mark R.
    Anders, Carey K.
    Connolly, Roisin M.
    Tweed, Carol
    Smith, Karen L.
    Khan, Imran
    Lipkowitz, Stanley
    Steeg, Patricia S.
    Zimmer, Alexandra S.
    CLINICAL CANCER RESEARCH, 2023, 29 (08) : 1450 - 1459
  • [3] Phase I study of T-DM1 and metronomic temozolomide in secondary prevention of HER2+breast cancer brain metastases following local radiation therapy
    Zimmer, Alexandra S.
    Steinberg, Seth
    Gilbert, Mark
    Armstrong, Terri
    Burton, Eric
    Houston, Nicole
    Smart, Dee Dee
    Biassou, Nadia
    Butman, John
    Brastianos, Priscilla K.
    Anders, Carey K.
    Lipkowitz, Stanley
    Steeg, Patricia S.
    CANCER RESEARCH, 2022, 82 (04)
  • [4] Activity of T-DM1 in HER2-positive breast cancer brain metastases
    Bartsch, Rupert
    Berghoff, Anna S.
    Vogl, Ursula
    Rudas, Margaretha
    Bergen, Elisabeth
    Gnant, Michael
    Dieckmann, Karin
    Pinker, Katja
    Bago-Horvath, Zsuzsanna
    Galid, Arik
    Oehler, Leopold
    Zielinksi, Christoph C.
    Steger, Guenther G.
    Preusser, Matthias
    CANCER RESEARCH, 2015, 75
  • [5] Activity of T-DM1 in HER2-positive breast cancer brain metastases
    Bartsch, R.
    Berghoff, A. S.
    Rudas, M.
    Bergen, E.
    Gnant, M.
    Dieckmann, K.
    Pinker, K.
    Zielinski, C. C.
    Preusser, M.
    Steger, G. G.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S184 - S184
  • [6] Activity of T-DM1 in Her2-positive breast cancer brain metastases
    Rupert Bartsch
    Anna S. Berghoff
    Ursula Vogl
    Margaretha Rudas
    Elisabeth Bergen
    Peter Dubsky
    Karin Dieckmann
    Katja Pinker
    Zsuzsanna Bago-Horvath
    Arik Galid
    Leopold Oehler
    Christoph C. Zielinski
    Michael Gnant
    Guenther G. Steger
    Matthias Preusser
    Clinical & Experimental Metastasis, 2015, 32 : 729 - 737
  • [7] T-DM1 in HER2-positive breast cancer brain metastases (BM).
    Bartsch, Rupert
    Berghoff, Anna Sophie
    Rudas, Margareta
    Bergen, Elisabeth
    Gnant, Michael
    Dieckmann, Karin
    Pinker, Katja
    Zielinski, Christoph
    Steger, Guenther G.
    Preusser, Matthias
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [8] Activity of T-DM1 in Her2-positive breast cancer brain metastases
    Bartsch, Rupert
    Berghoff, Anna S.
    Vogl, Ursula
    Rudas, Margaretha
    Bergen, Elisabeth
    Dubsky, Peter
    Dieckmann, Karin
    Pinker, Katja
    Bago-Horvath, Zsuzsanna
    Galid, Arik
    Oehler, Leopold
    Zielinski, Christoph C.
    Gnant, Michael
    Steger, Guenther G.
    Preusser, Matthias
    CLINICAL & EXPERIMENTAL METASTASIS, 2015, 32 (07) : 729 - 737
  • [9] T-DM1 is active in Her2-positive breast cancer brain metastases
    Bartsch, R.
    Berghoff, A.
    Rudas, M.
    Bergen, E.
    Gnant, M.
    Dieckmann, K.
    Pinker, K.
    Zielinski, C. C.
    Steger, G. G.
    Preusser, M.
    ONCOLOGY RESEARCH AND TREATMENT, 2014, 37 : 195 - 195
  • [10] RESPONSE TO T-DM1 IN HER2-POSITIVE BREAST CANCER BRAIN METASTASES (BM)
    Berghoff, A. S.
    Bartsch, R.
    Bergen, E.
    Rudas, M.
    Gnant, M.
    Dieckmann, K.
    Pinker, K.
    Zielinski, C. C.
    Steger, G. G.
    Preusser, M.
    NEURO-ONCOLOGY, 2014, 16
12345