Electrospun aligned PLLA/PCL/HA composite fibrous membranes and their in vitro degradation behaviors

被引：35
|
作者：
Liao, Guiying [1 ]
Jiang, Shengbin [2 ]
Xu, Xiaojun [2 ]
Ke, Yangli [1 ]
机构：
[1] China Univ Geosci, Fac Mat Sci & Chem, Wuhan 430074, Peoples R China
[2] Hubei Res Inst Chem, Wuhan 430074, Peoples R China
来源：
MATERIALS LETTERS | 2012年 / 82卷
关键词：
Electrospinning; Poly(L-lactide); Poly(epsilon-caprolactone); Hydroxyapatite; Polymeric composites; Biomaterials; HYDROXYAPATITE; NANOFIBERS; SCAFFOLDS;
D O I：
10.1016/j.matlet.2012.05.085
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Aligned poly(L-lactide) (PLLA)/poly(epsilon-caprolactone) (PCL)/hydroxyapatite (HA) composite fibrous membranes were fabricated by electrospinning. Their morphology, porosity, water contact angle and in vitro degradation behaviors were investigated. The scanning electron microscopy (SEM) and transmission electron microscope (TEM) indicated that the electrospun fibers are highly aligned and the HA are oriented along the fiber axis. The PLLA/PCL/HA composite fibers become thinner when HA are incorporated. The energy dispersion spectroscopy (EDS) demonstrated the existence of HA in the PLLA/PCL fibers. In addition, the larger porosity and higher hydrophilic properties induced by HA in the electrospun fibers have improved the biodegradation of the PLLA/PCL/HA fibrous membranes. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：159 / 162
页数：4
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