Rapid and convenient conversion of nitroarenes to anilines under microwave conditions using nonprecious metals in mildly acidic medium

被引：12

作者：

Keenan, Corey S. ^{[1
]}

Murphree, S. Shaun ^{[1
]}

机构：

[1] Allegheny Coll, Dept Chem, 520 N. Main St, Meadville, PA 16335 USA

来源：

SYNTHETIC COMMUNICATIONS | 2017年 / 47卷 / 11期

基金：

美国国家科学基金会;

关键词：

Anilines; iron; microwave chemistry; nitroarenes; reduction; zinc; CHEMOSELECTIVE REDUCTION; WATER;

D O I：

10.1080/00397911.2017.1310897

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitroarenes are reduced to the corresponding aniline derivatives using iron or zinc under mild conditions under microwave heating conditions. Mild acidity is provided by ammonium chloride in an aqueous methanol medium. The conditions are tolerant to other functional groups, with the exception of bromoalkyl derivatives, which yield complex reaction mixtures; otherwise, yields are generally quite high (80-99%).

引用

页码：1085 / 1089

页数：5

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