Spirolactone syntheses through a rhodium-catalyzed intramolecular C-H insertion reaction: model studies towards the synthesis of syringolides

被引：16
|
作者：
Villalobos, Mauricio Navarro [1 ]
Wood, John L. [1 ]
机构：
[1] Yale Univ, Sterling Chem Lab, New Haven, CT 06520 USA
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 47期
关键词：
Syringolides; Spirolactones; C-H insertion; Rhodium(II) stabilized carbene; Stereospecific; PLANT-DISEASE RESISTANCE; SYRINGAE PV TOMATO; GLYCOSIDIC ELICITORS; (-)-SYRINGOLIDE 1; SYRIBUTINS; AZIDE;
D O I：
10.1016/j.tetlet.2009.08.126
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Model studies towards the total synthesis of syringolides using a rhodium-catalyzed intramolecular C-H insertion reaction as the key step are described A highly stereospecific synthesis of spirolactones is achieved employing this methodology (C) 2009 Elsevier Ltd All rights reserved
引用
收藏
页码：6450 / 6453
页数：4
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