Chronic kidney disease in rheumatoid arthritis patients: prevalence, risks factors, histopathological variants

被引：1
|
作者：
Chebolareva, N., V [1 ]
Guliacv, S., V [1 ]
Androsova, T., V [1 ]
Milivanova, L. U. [1 ]
机构：
[1] IM Sechenov First Moscow State Med Univ, Minist Hlth Russian Federat, Sechenov Univ, Dept Internal Occupat Dis & Rheumatol, Moscow, Russia
来源：
TERAPEVTICHESKII ARKHIV | 2019年 / 91卷 / 05期
关键词：
rheumatoid arthritis; amyloidosis; chronic glomerulonephritis; chronic kidney disease; basic therapy; C-REACTIVE PROTEIN; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; FACTOR-ALPHA THERAPY; AMYLOIDOSIS SECONDARY; CARDIOVASCULAR EVENTS; RENAL PATHOLOGY; METHOTREXATE; INFLAMMATION;
D O I：
10.26442/00403660.2019.05.000255
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The present review is focused on risk factors of chronic kidney disease in rheumatoid arthritis (RA). According to recent data, the chronic kidney disease (CKD) in RA patients is more often than at patients without RA. It is closely associated with risk of cardiovascular disease and high mortality. Besides of general population risk factors of CKD, the activity of the disease is independent predictors of reduction in glomerular filtration rate less than 60 ml/min/1.73 m(2). In the review, histopathological variants and mechanisms of CKD on basis of international experience are also considered. Suppression of inflammation by basic therapy of RA and biological therapy have changed outcomes RA, prevalence, and structure of kidney involvement in recent years.
引用
收藏
页码：129 / 133
页数：5
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