Six months effective ocular drug levels and protection against laser CNV in a cynomolgus monkey after a single ocular administration of a biodegradable microsphere delivery system releasing a highly potent anti-VEGF domain antibody based molecule.

被引:0
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作者
Catchpole, Ian R. [1 ,2 ]
Adamson, Peter [2 ]
Wilde, Thomas [3 ]
Dobrzynski, Eric [3 ]
Sychertz, Caroline [3 ]
Polsky, Rodd [3 ]
Haworth, Richard [3 ]
Tang, Chi-Man [1 ]
Smal, Jos [4 ]
Van der Zwan, Judith [4 ]
机构
[1] BioPharm R&D, GSK, Stevenage, Herts, England
[2] GSK Ophthalmol, GSK, Stevenage, Herts, England
[3] GSK, PTS, King Of Prussia, PA USA
[4] Octoplus NV, Leiden, Netherlands
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中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
1498
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页数:3
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