Bioinspired and biocompatible adhesive coatings using poly(acrylic acid)-grafted dopamine

被引：13

作者：

Duan, Li Jie ^{[1
,2
]}

Liu, Ying ^{[1
]}

Kim, Jiheung ^{[3
]}

Chung, Dong June ^{[1
]}

机构：

[1] Sungkyunkwan Univ, Dept Polymer Sci & Engn, Suwon 440746, Gyeonggi, South Korea

[2] Changchun Univ Technol, Sch Chem & Life Sci, Changchun 130022, Peoples R China

[3] Sungkyunkwan Univ, Dept Chem Engn, Suwon 440746, Gyeonggi, South Korea

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 2013年 / 130卷 / 01期

关键词：

biomaterials; biomimetic; coatings; STENT; RESTENOSIS; SURFACES;

D O I：

10.1002/app.39133

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Poly(acrylic acid) (PAA) was grafted with dopamine to increase its adhesion force to metal surface. Nitinol plate surfaces were then modified by coating with PAA-g-dopamine. To synthesize PAA-g-dopamine, PAA was first activated by dicyclohexylcarbodiimide and N-hydroxysuccinimide (NHS) to form PAA-NHS. Dopamine was then copolymerized with PAA-NHS in an aqueous medium at pH 8.5. We propose to increase the adhesion of adhesive PAA-g-dopamine on nitinol to improve its durability. In this article, we studied wettability, surface elemental composition, and surface morphology. Biocompatibility was also assessed by L929 fibroblast cells in vitro. (c) 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013

引用

页码：131 / 137

页数：7

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