Acute myelitis and SARS-CoV-2 infection. A new etiology of myelitis?

被引：21

作者：

Aguila-Gordo, Daniel ^{[1
]}

Flores-Barragan, Jose Manuel ^{[2
]}

Ferragut-Lloret, Ferran ^{[3
]}

Portela-Gutierrez, Jaime ^{[3
]}

LaRosa-Salas, Beatriz ^{[4
]}

Porras-Leal, Lourdes ^{[4
]}

Villa Guzman, Jose Carlos ^{[3
]}

机构：

[1] Univ Hosp Ciudad Real, Cardiol Dept, Obispo Torija S-N, Ciudad Real 13005, Spain

[2] Hosp Gen Ciudad Real, Neurol Serv, Ciudad Real, Spain

[3] Hosp Gen Ciudad Real, Oncol Serv, Ciudad Real, Spain

[4] Hosp Gen Ciudad Real, Internal Med, Ciudad Real, Spain

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2020年 / 80卷

关键词：

SARS-CoV-2; COVID-19; Acute transverse myelitis; Neurological symptoms;

D O I：

10.1016/j.jocn.2020.07.074

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The etiological agent of coronavirus disease-19 (COVID-19), SARS-coronavirus-2 (SARS-CoV-2), emerged in Wuhan, China, and quickly spread worldwide leading the World Health Organization (WHO) to recognize it not only as a pandemic but also as an important thread to public health. Beyond respiratory symptoms, new neurological manifestations are being identified such as headache, ageusia, anosmia, encephalitis or acute cerebrovascular disease. Here we report the case of an acute transverse myelitis (TM) in a patient with SARS-CoV-2 infection detected by the nasopharyngeal swab technique but not in cerebrospinal fluid (CSF) analysis. Anti-herpes simplex virus (HSV) 1 and varicella-zoster IgM antibodies were not detected in serum samples and spinal and brain magnetic resonance imaging (MRI) showed no abnormal findings. This case remarks that COVID-19 nervous system damage could be caused by immune-mediated mechanisms. (C) 2020 Elsevier Ltd. All rights reserved.

引用

页码：280 / 281

页数：2

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